STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NAIPNLR family apoptosis inhibitory protein. (1403 aa)    
Predicted Functional Partners:
NLRC4
NLR family CARD domain containing 4.
  
 
0.956
AIM2
Absent in melanoma 2.
     
 0.935
CASP1
CASP1 isoform 4; Belongs to the peptidase C14A family.
   
 0.919
NLRP1
NLR family, pyrin domain containing 1.
    
0.910
NLRP6
NLR family pyrin domain containing 6.
    
 0.887
PYCARD
PYD and CARD domain containing.
    
 0.879
CASP5
CASP5 isoform 3; Belongs to the peptidase C14A family.
   
 0.859
TRADD
TNFRSF1A-associated via death domain.
   
 0.816
CIITA
Class II major histocompatibility complex transactivator.
    
 0.791
ENSPTRP00000043431
Caspase recruitment domain-containing protein 16/17/18.
   
 0.789
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.