STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPINT2T0106202 isoform 2. (252 aa)    
Predicted Functional Partners:
CK820_G0014442
PRSS3 isoform 6; Belongs to the peptidase S1 family.
   
 0.854
STK32A
Serine/threonine kinase 32A; Belongs to the protein kinase superfamily.
   
  
 0.836
RABGGTA
Rab geranylgeranyltransferase, alpha subunit.
      
 0.828
STAC2
SH3 and cysteine rich domain 2.
      
 0.796
VARS1
VARS isoform 2.
      
 0.781
HGF
Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.
    
 0.781
BIRC2
Baculoviral IAP repeat containing 2.
      
 0.759
ST14
Suppressor of tumorigenicity 14 protein homolog; Degrades extracellular matrix. Belongs to the peptidase S1 family.
   
 0.751
HGFAC
HGFAC isoform 1.
    
 0.729
HGFAC-2
HGFAC isoform 3.
    
 0.729
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.