STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CNTRLCentrosomal protein 110kDa. (2325 aa)    
Predicted Functional Partners:
PLK1
Serine/threonine-protein kinase PLK.
   
 0.896
NIN
NIN isoform 1.
   
 0.854
ODF2
Outer dense fiber of sperm tails 2.
   
 0.811
CEP170
Centrosomal protein 170kDa.
    
 0.811
CEP128
Centrosomal protein 128.
    
 0.785
CCDC120
CCDC120 isoform 4.
    
 0.706
TUBE1
Tubulin epsilon chain; Belongs to the tubulin family.
    
 
 0.680
SUN1
SUN1 isoform 2.
    
 
 0.678
SUN1-2
SUN1 isoform 10.
    
 
 0.678
SUN2
Sad1 and UNC84 domain containing 2.
    
 
 0.666
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.