| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DPP4 | GCG | ENSPTRP00000041681 | ENSPTRP00000049083 | Dipeptidyl-peptidase 4; Belongs to the peptidase S9B family. | GCG isoform 1. | 0.906 |
| DPP4 | GCGR | ENSPTRP00000041681 | ENSPTRP00000056951 | Dipeptidyl-peptidase 4; Belongs to the peptidase S9B family. | Glucagon receptor; Belongs to the G-protein coupled receptor 2 family. | 0.725 |
| DPP4 | GHRL | ENSPTRP00000041681 | ENSPTRP00000077851 | Dipeptidyl-peptidase 4; Belongs to the peptidase S9B family. | GHRL isoform 10. | 0.709 |
| DPP4 | GIP | ENSPTRP00000041681 | ENSPTRP00000015919 | Dipeptidyl-peptidase 4; Belongs to the peptidase S9B family. | Gastric inhibitory polypeptide. | 0.916 |
| DPP4 | GIPR | ENSPTRP00000041681 | ENSPTRP00000061947 | Dipeptidyl-peptidase 4; Belongs to the peptidase S9B family. | Gastric inhibitory polypeptide receptor; Belongs to the G-protein coupled receptor 2 family. | 0.731 |
| DPP4 | GLP1R | ENSPTRP00000041681 | ENSPTRP00000030970 | Dipeptidyl-peptidase 4; Belongs to the peptidase S9B family. | Glucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. | 0.887 |
| DPP4 | GLP2R | ENSPTRP00000041681 | ENSPTRP00000014927 | Dipeptidyl-peptidase 4; Belongs to the peptidase S9B family. | GLP2R isoform 2; Belongs to the G-protein coupled receptor 2 family. | 0.758 |
| DPP4 | GPR119 | ENSPTRP00000041681 | ENSPTRP00000045486 | Dipeptidyl-peptidase 4; Belongs to the peptidase S9B family. | G protein-coupled receptor 119; Belongs to the G-protein coupled receptor 1 family. | 0.657 |
| DPP4 | INS | ENSPTRP00000041681 | ENSPTRP00000077843 | Dipeptidyl-peptidase 4; Belongs to the peptidase S9B family. | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.697 |
| DPP4 | LEP | ENSPTRP00000041681 | ENSPTRP00000072740 | Dipeptidyl-peptidase 4; Belongs to the peptidase S9B family. | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] | 0.633 |
| GCG | DPP4 | ENSPTRP00000049083 | ENSPTRP00000041681 | GCG isoform 1. | Dipeptidyl-peptidase 4; Belongs to the peptidase S9B family. | 0.906 |
| GCG | GCGR | ENSPTRP00000049083 | ENSPTRP00000056951 | GCG isoform 1. | Glucagon receptor; Belongs to the G-protein coupled receptor 2 family. | 0.998 |
| GCG | GHRL | ENSPTRP00000049083 | ENSPTRP00000077851 | GCG isoform 1. | GHRL isoform 10. | 0.901 |
| GCG | GIP | ENSPTRP00000049083 | ENSPTRP00000015919 | GCG isoform 1. | Gastric inhibitory polypeptide. | 0.844 |
| GCG | GIPR | ENSPTRP00000049083 | ENSPTRP00000061947 | GCG isoform 1. | Gastric inhibitory polypeptide receptor; Belongs to the G-protein coupled receptor 2 family. | 0.953 |
| GCG | GLP1R | ENSPTRP00000049083 | ENSPTRP00000030970 | GCG isoform 1. | Glucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. | 0.998 |
| GCG | GLP2R | ENSPTRP00000049083 | ENSPTRP00000014927 | GCG isoform 1. | GLP2R isoform 2; Belongs to the G-protein coupled receptor 2 family. | 0.995 |
| GCG | GPR119 | ENSPTRP00000049083 | ENSPTRP00000045486 | GCG isoform 1. | G protein-coupled receptor 119; Belongs to the G-protein coupled receptor 1 family. | 0.915 |
| GCG | INS | ENSPTRP00000049083 | ENSPTRP00000077843 | GCG isoform 1. | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.883 |
| GCG | LEP | ENSPTRP00000049083 | ENSPTRP00000072740 | GCG isoform 1. | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] | 0.892 |
