STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (891 aa)    
Predicted Functional Partners:
UVRAG
UV radiation resistance associated protein.
    
 0.999
ATG14
ATG14 autophagy related 14 homolog.
    
 0.999
PIK3R4
Phosphoinositide-3-kinase, regulatory subunit 4.
   
 0.999
NRBF2
Nuclear receptor binding factor 2.
    
 0.999
BECN1
Beclin 1, autophagy related.
    
 0.998
BECN2
BECN2 isoform 1.
    
 0.997
AMBRA1
AMBRA1 isoform 6.
   
 0.997
ULK2
Serine/threonine-protein kinase; Serine/threonine-protein kinase involved in autophagy in response to starvation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily.
    
 0.994
RAB5A
RAB5A, member RAS oncogene family.
    
 0.993
BECN1-2
BECN1 isoform 3.
    
 0.993
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.