STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FREM1FREM1 isoform 1. (2179 aa)    
Predicted Functional Partners:
FREM2
FRAS1 related extracellular matrix 2.
   
0.970
FRAS1
Fraser extracellular matrix complex subunit 1.
   
0.947
ITGA8
Integrin subunit alpha 8; Belongs to the integrin alpha chain family.
   
 
 0.920
ITGB1
Integrin beta; Belongs to the integrin beta chain family.
    
  0.902
NPNT
NPNT isoform 10.
     
 0.876
GRIP1
Glutamate receptor interacting protein 1.
    
 
 0.684
SEMA3G
SEMA3G isoform 2; Belongs to the semaphorin family.
     
 0.610
CASKIN1
CASK interacting protein 1.
   
  0.584
ANKS1B
Ankyrin repeat and sterile alpha motif domain containing 1B.
   
  0.584
ANKS1A
Ankyrin repeat and sterile alpha motif domain containing 1A.
   
  0.584
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.