PTPRD protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPTRP00000085189	IL1RAP	ENSPTRP00000085189	ENSPTRP00000083273	annotation not available	Interleukin 1 receptor accessory protein.	0.837
ENSPTRP00000085189	IL1RAPL1	ENSPTRP00000085189	ENSPTRP00000037316	annotation not available	Interleukin-1 receptor accessory protein-like 1; May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. May activate the MAP kinase JNK (By similarity). Plays a role in neurite outgrowth (By similarity). During dendritic spine formation can bidirectionally induce pre- and post-synaptic differentiation of neurons by trans-synaptically binding to PTPRD (By similarity).	0.692
ENSPTRP00000085189	PPFIA1	ENSPTRP00000085189	ENSPTRP00000064702	annotation not available	PPFIA1 isoform 2.	0.798
ENSPTRP00000085189	PPFIA3	ENSPTRP00000085189	ENSPTRP00000074089	annotation not available	PTPRF interacting protein alpha 3.	0.553
ENSPTRP00000085189	PTPRD	ENSPTRP00000085189	ENSPTRP00000049466	annotation not available	PTPRD isoform 2.	0.884
ENSPTRP00000085189	SLITRK1	ENSPTRP00000085189	ENSPTRP00000010123	annotation not available	SLITRK1 isoform 1.	0.665
ENSPTRP00000085189	SLITRK2	ENSPTRP00000085189	ENSPTRP00000079242	annotation not available	SLITRK2 isoform 2.	0.548
ENSPTRP00000085189	SLITRK2-2	ENSPTRP00000085189	ENSPTRP00000086737	annotation not available	SLIT and NTRK like family member 2.	0.548
ENSPTRP00000085189	SLITRK3	ENSPTRP00000085189	ENSPTRP00000026832	annotation not available	SLITRK3 isoform 2.	0.564
IL1RAP	ENSPTRP00000085189	ENSPTRP00000083273	ENSPTRP00000085189	Interleukin 1 receptor accessory protein.	annotation not available	0.837
IL1RAP	PTPRD	ENSPTRP00000083273	ENSPTRP00000049466	Interleukin 1 receptor accessory protein.	PTPRD isoform 2.	0.962
IL1RAP	PTPRS	ENSPTRP00000083273	ENSPTRP00000017562	Interleukin 1 receptor accessory protein.	Protein tyrosine phosphatase receptor type S.	0.837
IL1RAPL1	ENSPTRP00000085189	ENSPTRP00000037316	ENSPTRP00000085189	Interleukin-1 receptor accessory protein-like 1; May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. May activate the MAP kinase JNK (By similarity). Plays a role in neurite outgrowth (By similarity). During dendritic spine formation can bidirectionally induce pre- and post-synaptic differentiation of neurons by trans-synaptically binding to PTPRD (By similarity).	annotation not available	0.692
IL1RAPL1	PTPRD	ENSPTRP00000037316	ENSPTRP00000049466	Interleukin-1 receptor accessory protein-like 1; May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. May activate the MAP kinase JNK (By similarity). Plays a role in neurite outgrowth (By similarity). During dendritic spine formation can bidirectionally induce pre- and post-synaptic differentiation of neurons by trans-synaptically binding to PTPRD (By similarity).	PTPRD isoform 2.	0.904
IL1RAPL1	PTPRS	ENSPTRP00000037316	ENSPTRP00000017562	Interleukin-1 receptor accessory protein-like 1; May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. May activate the MAP kinase JNK (By similarity). Plays a role in neurite outgrowth (By similarity). During dendritic spine formation can bidirectionally induce pre- and post-synaptic differentiation of neurons by trans-synaptically binding to PTPRD (By similarity).	Protein tyrosine phosphatase receptor type S.	0.692
IL1RAPL1	SLITRK1	ENSPTRP00000037316	ENSPTRP00000010123	Interleukin-1 receptor accessory protein-like 1; May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. May activate the MAP kinase JNK (By similarity). Plays a role in neurite outgrowth (By similarity). During dendritic spine formation can bidirectionally induce pre- and post-synaptic differentiation of neurons by trans-synaptically binding to PTPRD (By similarity).	SLITRK1 isoform 1.	0.579
IL1RAPL1	SLITRK2	ENSPTRP00000037316	ENSPTRP00000079242	Interleukin-1 receptor accessory protein-like 1; May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. May activate the MAP kinase JNK (By similarity). Plays a role in neurite outgrowth (By similarity). During dendritic spine formation can bidirectionally induce pre- and post-synaptic differentiation of neurons by trans-synaptically binding to PTPRD (By similarity).	SLITRK2 isoform 2.	0.736
IL1RAPL1	SLITRK2-2	ENSPTRP00000037316	ENSPTRP00000086737	Interleukin-1 receptor accessory protein-like 1; May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. May activate the MAP kinase JNK (By similarity). Plays a role in neurite outgrowth (By similarity). During dendritic spine formation can bidirectionally induce pre- and post-synaptic differentiation of neurons by trans-synaptically binding to PTPRD (By similarity).	SLIT and NTRK like family member 2.	0.736
IL1RAPL1	SLITRK3	ENSPTRP00000037316	ENSPTRP00000026832	Interleukin-1 receptor accessory protein-like 1; May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. May activate the MAP kinase JNK (By similarity). Plays a role in neurite outgrowth (By similarity). During dendritic spine formation can bidirectionally induce pre- and post-synaptic differentiation of neurons by trans-synaptically binding to PTPRD (By similarity).	SLITRK3 isoform 2.	0.667
PPFIA1	ENSPTRP00000085189	ENSPTRP00000064702	ENSPTRP00000085189	PPFIA1 isoform 2.	annotation not available	0.798