P2RX7 protein (Pan troglodytes) - STRING interaction network

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P2RX7

P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)

Predicted Functional Partners:

P2RX1

0.950

P2RX3

0.937

CHRNA7

0.905

GRIN2A

0.900

GRIN2C

0.900

PANX1

0.704

P2RX2

0.519

P2RX5

0.509

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHRNA7	GRIN2A	ENSPTRP00000011728	ENSPTRP00000055315	CHRNA7 isoform 7.	Glutamate receptor ionotropic, NMDA 2A; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition; channels containing GRIN1 and GRIN2A have higher sensitivity to glutamate and faster kineti [...]	0.923
CHRNA7	GRIN2C	ENSPTRP00000011728	ENSPTRP00000072438	CHRNA7 isoform 7.	GRIN2C isoform 4.	0.908
CHRNA7	P2RX1	ENSPTRP00000011728	ENSPTRP00000014652	CHRNA7 isoform 7.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.912
CHRNA7	P2RX3	ENSPTRP00000011728	ENSPTRP00000061714	CHRNA7 isoform 7.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.901
CHRNA7	P2RX7	ENSPTRP00000011728	ENSPTRP00000049853	CHRNA7 isoform 7.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.	0.905
GRIN2A	CHRNA7	ENSPTRP00000055315	ENSPTRP00000011728	Glutamate receptor ionotropic, NMDA 2A; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition; channels containing GRIN1 and GRIN2A have higher sensitivity to glutamate and faster kineti [...]	CHRNA7 isoform 7.	0.923
GRIN2A	GRIN2C	ENSPTRP00000055315	ENSPTRP00000072438	Glutamate receptor ionotropic, NMDA 2A; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition; channels containing GRIN1 and GRIN2A have higher sensitivity to glutamate and faster kineti [...]	GRIN2C isoform 4.	0.997
GRIN2A	P2RX1	ENSPTRP00000055315	ENSPTRP00000014652	Glutamate receptor ionotropic, NMDA 2A; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition; channels containing GRIN1 and GRIN2A have higher sensitivity to glutamate and faster kineti [...]	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.906
GRIN2A	P2RX3	ENSPTRP00000055315	ENSPTRP00000061714	Glutamate receptor ionotropic, NMDA 2A; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition; channels containing GRIN1 and GRIN2A have higher sensitivity to glutamate and faster kineti [...]	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.906
GRIN2A	P2RX7	ENSPTRP00000055315	ENSPTRP00000049853	Glutamate receptor ionotropic, NMDA 2A; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition; channels containing GRIN1 and GRIN2A have higher sensitivity to glutamate and faster kineti [...]	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.	0.900
GRIN2C	CHRNA7	ENSPTRP00000072438	ENSPTRP00000011728	GRIN2C isoform 4.	CHRNA7 isoform 7.	0.908
GRIN2C	GRIN2A	ENSPTRP00000072438	ENSPTRP00000055315	GRIN2C isoform 4.	Glutamate receptor ionotropic, NMDA 2A; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition; channels containing GRIN1 and GRIN2A have higher sensitivity to glutamate and faster kineti [...]	0.997
GRIN2C	P2RX1	ENSPTRP00000072438	ENSPTRP00000014652	GRIN2C isoform 4.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.907
GRIN2C	P2RX3	ENSPTRP00000072438	ENSPTRP00000061714	GRIN2C isoform 4.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.900
GRIN2C	P2RX7	ENSPTRP00000072438	ENSPTRP00000049853	GRIN2C isoform 4.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.	0.900
P2RX1	CHRNA7	ENSPTRP00000014652	ENSPTRP00000011728	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	CHRNA7 isoform 7.	0.912
P2RX1	GRIN2A	ENSPTRP00000014652	ENSPTRP00000055315	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	Glutamate receptor ionotropic, NMDA 2A; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition; channels containing GRIN1 and GRIN2A have higher sensitivity to glutamate and faster kineti [...]	0.906
P2RX1	GRIN2C	ENSPTRP00000014652	ENSPTRP00000072438	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	GRIN2C isoform 4.	0.907
P2RX1	P2RX2	ENSPTRP00000014652	ENSPTRP00000082887	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.	0.793
P2RX1	P2RX3	ENSPTRP00000014652	ENSPTRP00000061714	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.980