STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DEFB110Beta-defensin 110; Has antibacterial activity; Belongs to the beta-defensin family. (67 aa)    
Predicted Functional Partners:
DEFB113
Beta-defensin 113; Has antibacterial activity; Belongs to the beta-defensin family.
   
 
 0.671
DEFB105A
Beta-defensin 105A; Has antimicrobial activity; Belongs to the beta-defensin family.
  
 
 0.668
DEFB106A
Beta-defensin 106A; Has antibacterial activity. Acts as a ligand for C-C chemokine receptor CCR2.
  
 
 0.612
DEFB107A
Beta-defensin 107A; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.584
DEFB116
Beta-defensin 116; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.584
DEFB127
Beta-defensin 127; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.577
DEFB121
Beta-defensin 121; Has antibacterial activity; Belongs to the beta-defensin family.
   
 
 0.566
DEFB134
Beta-defensin 134; Has antibacterial activity; Belongs to the beta-defensin family.
  
  
 0.557
DEFB103A
Beta-defensin 103A; Exhibits antimicrobial activity against Gram-positive and Gram-negative bacteria; Belongs to the beta-defensin family.
     
 0.529
DEFB114
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
   
 
 0.512
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.