node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CD40LG | LTA | ENSPTRP00000077615 | ENSPTRP00000030651 | CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. | Lymphotoxin-alpha; Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM (By similarity). In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo (By similarity). | 0.691 |
CD40LG | LTB | ENSPTRP00000077615 | ENSPTRP00000050396 | CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. | Lymphotoxin-beta; Cytokine that binds to LTBR/TNFRSF3. May play a specific role in immune response regulation. Provides the membrane anchor for the attachment of the heterotrimeric complex to the cell surface (By similarity). | 0.683 |
CD40LG | LTBR | ENSPTRP00000077615 | ENSPTRP00000007817 | CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. | Lymphotoxin beta receptor (TNFR superfamily, member 3). | 0.800 |
CD40LG | RELB | ENSPTRP00000077615 | ENSPTRP00000088356 | CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. | RELB isoform 3. | 0.470 |
CD40LG | TNFRSF13C | ENSPTRP00000077615 | ENSPTRP00000024871 | CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. | TNF receptor superfamily member 13C. | 0.824 |
CD40LG | TNFRSF14 | ENSPTRP00000077615 | ENSPTRP00000000096 | CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. | Tumor necrosis factor receptor superfamily, member 14 (Herpesvirus entry mediator). | 0.732 |
CD40LG | TNFRSF1B | ENSPTRP00000077615 | ENSPTRP00000000311 | CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. | Tumor necrosis factor receptor superfamily, member 1B. | 0.703 |
CD40LG | TNFSF13B | ENSPTRP00000077615 | ENSPTRP00000010240 | CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. | Tumor necrosis factor ligand 7A; Belongs to the tumor necrosis factor family. | 0.830 |
LST1 | LTA | ENSPTRP00000067047 | ENSPTRP00000030651 | Leukocyte specific transcript 1. | Lymphotoxin-alpha; Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM (By similarity). In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo (By similarity). | 0.572 |
LST1 | LTB | ENSPTRP00000067047 | ENSPTRP00000050396 | Leukocyte specific transcript 1. | Lymphotoxin-beta; Cytokine that binds to LTBR/TNFRSF3. May play a specific role in immune response regulation. Provides the membrane anchor for the attachment of the heterotrimeric complex to the cell surface (By similarity). | 0.737 |
LTA | CD40LG | ENSPTRP00000030651 | ENSPTRP00000077615 | Lymphotoxin-alpha; Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM (By similarity). In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo (By similarity). | CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. | 0.691 |
LTA | LST1 | ENSPTRP00000030651 | ENSPTRP00000067047 | Lymphotoxin-alpha; Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM (By similarity). In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo (By similarity). | Leukocyte specific transcript 1. | 0.572 |
LTA | LTB | ENSPTRP00000030651 | ENSPTRP00000050396 | Lymphotoxin-alpha; Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM (By similarity). In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo (By similarity). | Lymphotoxin-beta; Cytokine that binds to LTBR/TNFRSF3. May play a specific role in immune response regulation. Provides the membrane anchor for the attachment of the heterotrimeric complex to the cell surface (By similarity). | 0.999 |
LTA | LTBR | ENSPTRP00000030651 | ENSPTRP00000007817 | Lymphotoxin-alpha; Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM (By similarity). In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo (By similarity). | Lymphotoxin beta receptor (TNFR superfamily, member 3). | 0.998 |
LTA | RELB | ENSPTRP00000030651 | ENSPTRP00000088356 | Lymphotoxin-alpha; Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM (By similarity). In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo (By similarity). | RELB isoform 3. | 0.493 |
LTA | TNFRSF13C | ENSPTRP00000030651 | ENSPTRP00000024871 | Lymphotoxin-alpha; Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM (By similarity). In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo (By similarity). | TNF receptor superfamily member 13C. | 0.503 |
LTA | TNFRSF14 | ENSPTRP00000030651 | ENSPTRP00000000096 | Lymphotoxin-alpha; Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM (By similarity). In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo (By similarity). | Tumor necrosis factor receptor superfamily, member 14 (Herpesvirus entry mediator). | 0.989 |
LTA | TNFRSF1B | ENSPTRP00000030651 | ENSPTRP00000000311 | Lymphotoxin-alpha; Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM (By similarity). In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo (By similarity). | Tumor necrosis factor receptor superfamily, member 1B. | 0.994 |
LTA | TNFSF13B | ENSPTRP00000030651 | ENSPTRP00000010240 | Lymphotoxin-alpha; Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM (By similarity). In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo (By similarity). | Tumor necrosis factor ligand 7A; Belongs to the tumor necrosis factor family. | 0.575 |
LTB | CD40LG | ENSPTRP00000050396 | ENSPTRP00000077615 | Lymphotoxin-beta; Cytokine that binds to LTBR/TNFRSF3. May play a specific role in immune response regulation. Provides the membrane anchor for the attachment of the heterotrimeric complex to the cell surface (By similarity). | CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. | 0.683 |