STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GPX6Glutathione peroxidase 6 precursor. (220 aa)    
Predicted Functional Partners:
GSR
Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  
 0.989
PRDX6
PRDX6 isoform 1.
   
 0.945
PPARGC1A
PPARG coactivator 1 alpha.
     
 0.943
GPX4
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
  
  
0.931
GPX8
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
  
  
0.930
GSS
Glutathione synthetase.
   
 
 0.926
GPX7
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
  
  
0.926
ALOX15
Arachidonate 15-lipoxygenase.
   
 
 0.918
ALOX15B
Arachidonate 15-lipoxygenase, type B.
   
 0.909
GPX1
Glutathione peroxidase 1; Protects the hemoglobin in erythrocytes from oxidative breakdown.
  
  
0.908
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.