| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CD22 | CD72 | ENSPTRP00000018557 | ENSPTRP00000035770 | B-cell receptor CD22; Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6- linked sialic acid (By similarity). Upon ligand-induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that b [...] | CD72 isoform 2. | 0.766 |
| CD22 | PTPN6 | ENSPTRP00000018557 | ENSPTRP00000050501 | B-cell receptor CD22; Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6- linked sialic acid (By similarity). Upon ligand-induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that b [...] | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.994 |
| CD22 | SYK | ENSPTRP00000018557 | ENSPTRP00000074883 | B-cell receptor CD22; Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6- linked sialic acid (By similarity). Upon ligand-induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that b [...] | Tyrosine-protein kinase. | 0.880 |
| CD72 | CD22 | ENSPTRP00000035770 | ENSPTRP00000018557 | CD72 isoform 2. | B-cell receptor CD22; Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6- linked sialic acid (By similarity). Upon ligand-induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that b [...] | 0.766 |
| CD72 | PECAM1 | ENSPTRP00000035770 | ENSPTRP00000080846 | CD72 isoform 2. | Platelet/endothelial cell adhesion molecule. | 0.500 |
| CD72 | PTPN6 | ENSPTRP00000035770 | ENSPTRP00000050501 | CD72 isoform 2. | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.981 |
| JAK2 | KDR | ENSPTRP00000082180 | ENSPTRP00000027639 | Tyrosine-protein kinase. | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | 0.917 |
| JAK2 | PIK3R1 | ENSPTRP00000082180 | ENSPTRP00000076964 | Tyrosine-protein kinase. | Phosphoinositide-3-kinase, regulatory subunit 1 (Alpha). | 0.990 |
| JAK2 | PTPN6 | ENSPTRP00000082180 | ENSPTRP00000050501 | Tyrosine-protein kinase. | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.995 |
| JAK2 | SYK | ENSPTRP00000082180 | ENSPTRP00000074883 | Tyrosine-protein kinase. | Tyrosine-protein kinase. | 0.881 |
| KDR | JAK2 | ENSPTRP00000027639 | ENSPTRP00000082180 | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Tyrosine-protein kinase. | 0.917 |
| KDR | PECAM1 | ENSPTRP00000027639 | ENSPTRP00000080846 | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Platelet/endothelial cell adhesion molecule. | 0.979 |
| KDR | PIK3R1 | ENSPTRP00000027639 | ENSPTRP00000076964 | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Phosphoinositide-3-kinase, regulatory subunit 1 (Alpha). | 0.991 |
| KDR | PTPN6 | ENSPTRP00000027639 | ENSPTRP00000050501 | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.983 |
| LCP2 | PECAM1 | ENSPTRP00000029923 | ENSPTRP00000080846 | Lymphocyte cytosolic protein 2. | Platelet/endothelial cell adhesion molecule. | 0.438 |
| LCP2 | PIK3R1 | ENSPTRP00000029923 | ENSPTRP00000076964 | Lymphocyte cytosolic protein 2. | Phosphoinositide-3-kinase, regulatory subunit 1 (Alpha). | 0.840 |
| LCP2 | PTPN6 | ENSPTRP00000029923 | ENSPTRP00000050501 | Lymphocyte cytosolic protein 2. | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.977 |
| LCP2 | SYK | ENSPTRP00000029923 | ENSPTRP00000074883 | Lymphocyte cytosolic protein 2. | Tyrosine-protein kinase. | 0.997 |
| LOC458036 | PECAM1 | ENSPTRP00000022540 | ENSPTRP00000080846 | T0061165 isoform 1. | Platelet/endothelial cell adhesion molecule. | 0.916 |
| LOC458036 | PTPN6 | ENSPTRP00000022540 | ENSPTRP00000050501 | T0061165 isoform 1. | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.987 |
