STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LIPNLipase; Belongs to the AB hydrolase superfamily. Lipase family. (398 aa)    
Predicted Functional Partners:
CYP4F22
Cytochrome P450 family 4 subfamily F member 22; Belongs to the cytochrome P450 family.
  
 
 0.785
ABCA12
ATP binding cassette subfamily A member 12.
  
  
 0.766
NIPAL4
NIPA like domain containing 4.
      
 0.756
LIPG
Lipase G, endothelial type.
   
  
 0.734
PNPLA1
Patatin like phospholipase domain containing 1.
    
 
 0.728
CERS3
CERS3 isoform 1.
   
  
 0.707
PCSK5
PCSK5 isoform 1; Belongs to the peptidase S8 family.
  
  
 0.679
SP6
Sp6 transcription factor.
   
  
 0.678
LRP5
Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.
      
 0.674
ACRV1
Acrosomal vesicle protein 1.
   
 0.629
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.