STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PPM1LProtein phosphatase, Mg2+/Mn2+ dependent 1L. (360 aa)    
Predicted Functional Partners:
BCKDHB
BCKDHB isoform 1.
   
 0.704
VAPA
VAPA isoform 3.
   
 0.661
AANAT
Serotonin N-acetyltransferase; Controls the night/day rhythm of melatonin production in the pineal gland. Catalyzes the N-acetylation of serotonin into N- acetylserotonin, the penultimate step in the synthesis of melatonin (By similarity); Belongs to the acetyltransferase family. AANAT subfamily.
    
   0.630
VAPB
VAMP (Vesicle-associated membrane protein)-associated protein B and C.
   
 0.629
BCKDHA
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3); Belongs to the BCKDHA family.
   
 0.625
DBT
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
   
 0.624
LOC101057829
ZNF74 isoform 8.
   
 0.582
MTFMT
Mitochondrial methionyl-tRNA formyltransferase.
  
   0.563
MAP3K7
Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
  
 0.559
PPP5C
Serine/threonine-protein phosphatase.
    
 
 0.551
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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