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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)    
Predicted Functional Partners:
PHLPP2
PHLPP2 isoform 2.
    
 0.986
PHLPP1
PH domain and leucine rich repeat protein phosphatase 1.
    
 0.983
MTOR
Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.
    
 0.980
PIK3CG
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family.
    
 0.974
FOXO1
FOXO1 isoform 1.
    
 0.973
PIK3R1
Phosphoinositide-3-kinase, regulatory subunit 1 (Alpha).
   
 0.973
CDKN1B
Cyclin-dependent kinase inhibitor 1B (P27, Kip1).
    
 0.971
TSC1
TSC complex subunit 1.
    
 0.971
PIK3R3
Phosphoinositide-3-kinase, regulatory subunit 3 (Gamma).
   
 0.971
AKT1S1
AKT1 substrate 1 (Proline-rich).
   
 0.970
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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