STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BOCBOC cell adhesion associated, oncogene regulated. (1115 aa)    
Predicted Functional Partners:
PTCH1
PTCH1 isoform 8.
    
 0.996
IHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.994
DHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.994
CDON
Cell adhesion associated, oncogene regulated.
    
0.990
SHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.989
PTCH2
PTCH2 isoform 3.
    
 0.976
GAS1
Growth arrest-specific 1.
    
 0.963
SMO
SMO isoform 1; Belongs to the G-protein coupled receptor Fz/Smo family.
   
 0.952
LRP2
LRP2 isoform 1.
     
 0.906
CDH15
CDH15 isoform 1; Cadherins are calcium-dependent cell adhesion proteins.
   
 0.656
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.