STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TICRRTICRR isoform 1. (1911 aa)    
Predicted Functional Partners:
TOPBP1
Topoisomerase (DNA) II binding protein 1.
    
 
 0.991
MTBP
Mdm2, transformed 3T3 cell double minute 2, p53 binding protein binding protein, 104kDa.
   
 0.920
CDC45
CDC45 isoform 5.
   
  
 0.896
RECQL4
RECQL4 isoform 3.
  
 
 0.881
MCM10
Minichromosome maintenance complex component 10.
   
  
 0.799
EXO1
EXO1 isoform 1.
  
 
 0.789
DBF4-2
DBF4 zinc finger.
   
  
 0.779
DBF4
DBF4 isoform 2.
   
  
 0.777
MCM4
DNA helicase; Belongs to the MCM family.
   
  
 0.770
POLG2
Polymerase (DNA directed), gamma 2, accessory subunit.
   
 
 0.747
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.