ASPM protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASPM	BUB1	ENSPTRP00000051373	ENSPTRP00000074938	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).	BUB1 isoform 1.	0.971
ASPM	BUB1B	ENSPTRP00000051373	ENSPTRP00000077805	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).	BUB1B-PAK6 isoform 4.	0.969
ASPM	CENPE	ENSPTRP00000051373	ENSPTRP00000090205	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).	CENPE isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.958
ASPM	CENPF	ENSPTRP00000051373	ENSPTRP00000003323	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).	Centromere protein F, 350/400kDa (Mitosin).	0.972
ASPM	DLGAP5	ENSPTRP00000051373	ENSPTRP00000010806	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).	Discs, large homolog-associated protein 5.	0.961
ASPM	KIF11	ENSPTRP00000051373	ENSPTRP00000004812	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).	Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.972
ASPM	KIF15	ENSPTRP00000051373	ENSPTRP00000042807	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).	Kinesin family member 15; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.963
ASPM	KIF23	ENSPTRP00000051373	ENSPTRP00000012362	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.961
ASPM	NCAPG	ENSPTRP00000051373	ENSPTRP00000027454	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).	Non-SMC condensin I complex, subunit G.	0.950
ASPM	TOP2A	ENSPTRP00000051373	ENSPTRP00000015554	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	0.978
BUB1	ASPM	ENSPTRP00000074938	ENSPTRP00000051373	BUB1 isoform 1.	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).	0.971
BUB1	BUB1B	ENSPTRP00000074938	ENSPTRP00000077805	BUB1 isoform 1.	BUB1B-PAK6 isoform 4.	0.998
BUB1	CENPE	ENSPTRP00000074938	ENSPTRP00000090205	BUB1 isoform 1.	CENPE isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.998
BUB1	CENPF	ENSPTRP00000074938	ENSPTRP00000003323	BUB1 isoform 1.	Centromere protein F, 350/400kDa (Mitosin).	0.997
BUB1	DLGAP5	ENSPTRP00000074938	ENSPTRP00000010806	BUB1 isoform 1.	Discs, large homolog-associated protein 5.	0.975
BUB1	KIF11	ENSPTRP00000074938	ENSPTRP00000004812	BUB1 isoform 1.	Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.982
BUB1	KIF15	ENSPTRP00000074938	ENSPTRP00000042807	BUB1 isoform 1.	Kinesin family member 15; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.945
BUB1	KIF23	ENSPTRP00000074938	ENSPTRP00000012362	BUB1 isoform 1.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.946
BUB1	NCAPG	ENSPTRP00000074938	ENSPTRP00000027454	BUB1 isoform 1.	Non-SMC condensin I complex, subunit G.	0.958
BUB1	TOP2A	ENSPTRP00000074938	ENSPTRP00000015554	BUB1 isoform 1.	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	0.965