RO60 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGO2	RO60	ENSPTRP00000035263	ENSPTRP00000070548	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	TROVE2 isoform 5.	0.672
B3GALT2	RO60	ENSPTRP00000064523	ENSPTRP00000070548	Hexosyltransferase.	TROVE2 isoform 5.	0.646
COG3	RO60	ENSPTRP00000046349	ENSPTRP00000070548	Component of oligomeric golgi complex 3.	TROVE2 isoform 5.	0.645
HARS2	RO60	ENSPTRP00000068282	ENSPTRP00000070548	Histidyl-tRNA synthetase 2, mitochondrial (Putative).	TROVE2 isoform 5.	0.596
HSPA4	RO60	ENSPTRP00000029477	ENSPTRP00000070548	Heat shock protein family A (Hsp70) member 4.	TROVE2 isoform 5.	0.597
HSPA4	TRIM21	ENSPTRP00000029477	ENSPTRP00000005673	Heat shock protein family A (Hsp70) member 4.	Tripartite motif containing 21.	0.614
LOC100609987	RO60	ENSPTRP00000079176	ENSPTRP00000070548	Lupus La protein pseudogene.	TROVE2 isoform 5.	0.817
LOC100609987	TRIM21	ENSPTRP00000079176	ENSPTRP00000005673	Lupus La protein pseudogene.	Tripartite motif containing 21.	0.598
RO60	AGO2	ENSPTRP00000070548	ENSPTRP00000035263	TROVE2 isoform 5.	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	0.672
RO60	B3GALT2	ENSPTRP00000070548	ENSPTRP00000064523	TROVE2 isoform 5.	Hexosyltransferase.	0.646
RO60	COG3	ENSPTRP00000070548	ENSPTRP00000046349	TROVE2 isoform 5.	Component of oligomeric golgi complex 3.	0.645
RO60	HARS2	ENSPTRP00000070548	ENSPTRP00000068282	TROVE2 isoform 5.	Histidyl-tRNA synthetase 2, mitochondrial (Putative).	0.596
RO60	HSPA4	ENSPTRP00000070548	ENSPTRP00000029477	TROVE2 isoform 5.	Heat shock protein family A (Hsp70) member 4.	0.597
RO60	LOC100609987	ENSPTRP00000070548	ENSPTRP00000079176	TROVE2 isoform 5.	Lupus La protein pseudogene.	0.817
RO60	SSB	ENSPTRP00000070548	ENSPTRP00000021558	TROVE2 isoform 5.	Small RNA binding exonuclease protection factor La.	0.817
RO60	TRIM21	ENSPTRP00000070548	ENSPTRP00000005673	TROVE2 isoform 5.	Tripartite motif containing 21.	0.933
RO60	XPO7	ENSPTRP00000070548	ENSPTRP00000072544	TROVE2 isoform 5.	XPO7 isoform 2.	0.590
RO60	ZBP1	ENSPTRP00000070548	ENSPTRP00000088120	TROVE2 isoform 5.	Z-DNA binding protein 1.	0.599
SSB	RO60	ENSPTRP00000021558	ENSPTRP00000070548	Small RNA binding exonuclease protection factor La.	TROVE2 isoform 5.	0.817
SSB	TRIM21	ENSPTRP00000021558	ENSPTRP00000005673	Small RNA binding exonuclease protection factor La.	Tripartite motif containing 21.	0.598