close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PDIA3Protein disulfide-isomerase. (505 aa)    
Predicted Functional Partners:
CALR
Calreticulin.
   
 0.998
TAPBP
TAP binding protein.
   
 0.997
TAP1
TAP1 isoform 1.
   
 0.963
PATR-AL
Major histocompatibility complex, class I, AL precursor.
    
 0.961
TAP2
Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP).
   
 0.946
PATR-E
Patr class I histocompatibility antigen, alpha chain E; Preferably binds to a peptide derived from the signal sequence of most HLA-A, -B, -C and -G molecules.
    
 0.944
CANX
CANX isoform 1.
   
 0.941
PATR-F
Patr class I histocompatibility antigen, CH28 alpha chain; Involved in the presentation of foreign antigens to the immune system.
    
 0.938
ENSPTRP00000066786
LOW QUALITY PROTEIN: HLA class I histocompatibility antigen, A-3 alpha chain.
    
 0.938
HSPA5
Heat shock 70kDa protein 5 (Glucose-regulated protein, 78kDa); Belongs to the heat shock protein 70 family.
   
 0.929
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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