| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C1QA | CD4 | ENSPTRP00000059755 | ENSPTRP00000054833 | Complement C1q A chain. | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | 0.477 |
| C1QA | ENSPTRP00000051627 | ENSPTRP00000059755 | ENSPTRP00000051627 | Complement C1q A chain. | annotation not available | 0.643 |
| C1QA | FCER1G | ENSPTRP00000059755 | ENSPTRP00000051638 | Complement C1q A chain. | Fc fragment of IgE receptor Ig. | 0.692 |
| C1QA | TYROBP | ENSPTRP00000059755 | ENSPTRP00000018632 | Complement C1q A chain. | TYRO protein tyrosine kinase-binding protein; Adapter protein which non-covalently associates with activating receptors found on the surface of a variety of immune cells to mediate signaling and cell activation following ligand binding by the receptors (By similarity). TYROBP is tyrosine-phosphorylated in the ITAM domain following ligand binding by the associated receptors which leads to activation of additional tyrosine kinases and subsequent cell activation (By similarity). Also has an inhibitory role in some cells (By similarity). Non-covalently associates with activating receptors [...] | 0.792 |
| CD19 | CD247 | ENSPTRP00000079367 | ENSPTRP00000044167 | CD19 isoform 1. | CD247 isoform 2. | 0.563 |
| CD19 | CD38 | ENSPTRP00000079367 | ENSPTRP00000027436 | CD19 isoform 1. | CD38 isoform 1. | 0.851 |
| CD19 | CD4 | ENSPTRP00000079367 | ENSPTRP00000054833 | CD19 isoform 1. | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | 0.953 |
| CD19 | CD86 | ENSPTRP00000079367 | ENSPTRP00000026356 | CD19 isoform 1. | CD86 isoform 3. | 0.718 |
| CD19 | ENSPTRP00000051627 | ENSPTRP00000079367 | ENSPTRP00000051627 | CD19 isoform 1. | annotation not available | 0.537 |
| CD19 | SELL | ENSPTRP00000079367 | ENSPTRP00000002764 | CD19 isoform 1. | L-selectin; Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia; Belongs to the selectin/LECAM family. | 0.778 |
| CD19 | TNF | ENSPTRP00000079367 | ENSPTRP00000069905 | CD19 isoform 1. | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] | 0.684 |
| CD247 | CD19 | ENSPTRP00000044167 | ENSPTRP00000079367 | CD247 isoform 2. | CD19 isoform 1. | 0.563 |
| CD247 | CD38 | ENSPTRP00000044167 | ENSPTRP00000027436 | CD247 isoform 2. | CD38 isoform 1. | 0.405 |
| CD247 | CD4 | ENSPTRP00000044167 | ENSPTRP00000054833 | CD247 isoform 2. | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | 0.712 |
| CD247 | ENSPTRP00000051627 | ENSPTRP00000044167 | ENSPTRP00000051627 | CD247 isoform 2. | annotation not available | 0.558 |
| CD247 | FCER1G | ENSPTRP00000044167 | ENSPTRP00000051638 | CD247 isoform 2. | Fc fragment of IgE receptor Ig. | 0.556 |
| CD247 | TYROBP | ENSPTRP00000044167 | ENSPTRP00000018632 | CD247 isoform 2. | TYRO protein tyrosine kinase-binding protein; Adapter protein which non-covalently associates with activating receptors found on the surface of a variety of immune cells to mediate signaling and cell activation following ligand binding by the receptors (By similarity). TYROBP is tyrosine-phosphorylated in the ITAM domain following ligand binding by the associated receptors which leads to activation of additional tyrosine kinases and subsequent cell activation (By similarity). Also has an inhibitory role in some cells (By similarity). Non-covalently associates with activating receptors [...] | 0.673 |
| CD38 | CD19 | ENSPTRP00000027436 | ENSPTRP00000079367 | CD38 isoform 1. | CD19 isoform 1. | 0.851 |
| CD38 | CD247 | ENSPTRP00000027436 | ENSPTRP00000044167 | CD38 isoform 1. | CD247 isoform 2. | 0.405 |
| CD38 | CD4 | ENSPTRP00000027436 | ENSPTRP00000054833 | CD38 isoform 1. | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | 0.957 |
