STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAE1RAE1 RNA export 1 homolog. (368 aa)    
Predicted Functional Partners:
NUP98
Nucleoporin 98kDa.
   
 0.999
NXF1
Nuclear RNA export factor 1.
    
 0.994
NUP214
NUP214 isoform 1.
    
 0.987
GLE1
GLE1 RNA export mediator homolog.
   
 0.976
NXF5
NXF5 isoform 2.
    
 0.976
CK820_G0055937
NXF2B isoform 3.
    
 0.976
NUP88
NUP88 isoform 1.
   
 0.969
NUP153
NUP153 isoform 1.
    
 0.959
NUP85
Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC).
   
 0.951
RANBP2-2
E3 SUMO-protein ligase RanBP2; E3 SUMO-protein ligase which facilitates SUMO1 and SUMO2 conjugation by UBE2I. Involved in transport factor (Ran-GTP, karyopherin)-mediated protein import via the F-G repeat-containing domain which acts as a docking site for substrates. Component of the nuclear export pathway. Specific docking site for the nuclear export factor exportin-1. Sumoylates PML at 'Lys-490' which is essential for the proper assembly of PML-NB. Recruits BICD2 to the nuclear envelope and cytoplasmic stacks of nuclear pore complex known as annulate lamellae during G2 phase of cell [...]
   
 0.950
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.