ISCA2 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ISCA2

Iron-sulfur cluster assembly 2 homolog. (154 aa)

Predicted Functional Partners:

LOC107973768

0.896

ENSPTRP00000062719

0.895

CK820_G0036261

0.895

CK820_G0036261-2

0.810

IBA57

0.798

LOC738449

0.784

ISCU

0.784

GLRX5

0.781

NFU1

0.776

NFS1

0.684

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CK820_G0036261	GLRX5	ENSPTRP00000072702	ENSPTRP00000011409	HESB-like domain-containing protein 2, mitochondrial.	GLRX5 isoform 2.	0.704
CK820_G0036261	IBA57	ENSPTRP00000072702	ENSPTRP00000003502	HESB-like domain-containing protein 2, mitochondrial.	IBA57, iron-sulfur cluster assembly homolog.	0.678
CK820_G0036261	ISCA2	ENSPTRP00000072702	ENSPTRP00000052565	HESB-like domain-containing protein 2, mitochondrial.	Iron-sulfur cluster assembly 2 homolog.	0.895
CK820_G0036261	ISCU	ENSPTRP00000072702	ENSPTRP00000081100	HESB-like domain-containing protein 2, mitochondrial.	ISCU isoform 5; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	0.748
CK820_G0036261	LOC738449	ENSPTRP00000072702	ENSPTRP00000009171	HESB-like domain-containing protein 2, mitochondrial.	Iron-sulfur cluster scaffold homolog; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	0.748
CK820_G0036261	NFS1	ENSPTRP00000072702	ENSPTRP00000063061	HESB-like domain-containing protein 2, mitochondrial.	NFS1 nitrogen fixation 1 homolog.	0.666
CK820_G0036261	NFU1	ENSPTRP00000072702	ENSPTRP00000076245	HESB-like domain-containing protein 2, mitochondrial.	NFU1 iron-sulfur cluster scaffold homolog.	0.734
CK820_G0036261-2	GLRX5	ENSPTRP00000073677	ENSPTRP00000011409	ISCA1 isoform 2.	GLRX5 isoform 2.	0.704
CK820_G0036261-2	IBA57	ENSPTRP00000073677	ENSPTRP00000003502	ISCA1 isoform 2.	IBA57, iron-sulfur cluster assembly homolog.	0.678
CK820_G0036261-2	ISCA2	ENSPTRP00000073677	ENSPTRP00000052565	ISCA1 isoform 2.	Iron-sulfur cluster assembly 2 homolog.	0.810
CK820_G0036261-2	ISCU	ENSPTRP00000073677	ENSPTRP00000081100	ISCA1 isoform 2.	ISCU isoform 5; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	0.748
CK820_G0036261-2	LOC738449	ENSPTRP00000073677	ENSPTRP00000009171	ISCA1 isoform 2.	Iron-sulfur cluster scaffold homolog; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	0.748
CK820_G0036261-2	NFS1	ENSPTRP00000073677	ENSPTRP00000063061	ISCA1 isoform 2.	NFS1 nitrogen fixation 1 homolog.	0.666
CK820_G0036261-2	NFU1	ENSPTRP00000073677	ENSPTRP00000076245	ISCA1 isoform 2.	NFU1 iron-sulfur cluster scaffold homolog.	0.734
ENSPTRP00000062719	GLRX5	ENSPTRP00000062719	ENSPTRP00000011409	annotation not available	GLRX5 isoform 2.	0.704
ENSPTRP00000062719	IBA57	ENSPTRP00000062719	ENSPTRP00000003502	annotation not available	IBA57, iron-sulfur cluster assembly homolog.	0.678
ENSPTRP00000062719	ISCA2	ENSPTRP00000062719	ENSPTRP00000052565	annotation not available	Iron-sulfur cluster assembly 2 homolog.	0.895
ENSPTRP00000062719	ISCU	ENSPTRP00000062719	ENSPTRP00000081100	annotation not available	ISCU isoform 5; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	0.748
ENSPTRP00000062719	LOC738449	ENSPTRP00000062719	ENSPTRP00000009171	annotation not available	Iron-sulfur cluster scaffold homolog; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	0.748
ENSPTRP00000062719	NFS1	ENSPTRP00000062719	ENSPTRP00000063061	annotation not available	NFS1 nitrogen fixation 1 homolog.	0.666