close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DEFB136Beta-defensin 136; Has antibacterial activity; Belongs to the beta-defensin family. (78 aa)    
Predicted Functional Partners:
DEFB130
Beta-defensin 130; Antimicrobial host-defense peptide. Belongs to the beta-defensin family.
  
  
 0.874
DEFB135
Beta-defensin 135; Has antibacterial activity; Belongs to the beta-defensin family.
  
  
 0.834
IARS1
Isoleucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
      
 0.761
DEFB113
Beta-defensin 113; Has antibacterial activity; Belongs to the beta-defensin family.
  
  
 0.753
DEFB124
Beta-defensin 124; Has antibacterial activity; Belongs to the beta-defensin family.
  
  
 0.728
XKR6
XK-related protein.
      
 0.672
DEFB119
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.597
DEFB134
Beta-defensin 134; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.584
ENSPTRP00000059204
annotation not available
  
  
  0.529
SPAG11B
Sperm-associated antigen 11; Belongs to the SPAG11 family.
      
 0.510
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.