EBPL protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP6V0D1	EBPL	ENSPTRP00000014055	ENSPTRP00000053511	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family.	Emopamil binding protein-like.	0.464
DHCR24	EBPL	ENSPTRP00000001349	ENSPTRP00000053511	24-dehydrocholesterol reductase.	Emopamil binding protein-like.	0.484
DHCR24	SC5D	ENSPTRP00000001349	ENSPTRP00000066518	24-dehydrocholesterol reductase.	Sterol-C5-desaturase; Belongs to the sterol desaturase family.	0.980
DLEU7	EBPL	ENSPTRP00000088785	ENSPTRP00000053511	Deleted in lymphocytic leukemia 7.	Emopamil binding protein-like.	0.465
DLEU7	ITM2B	ENSPTRP00000088785	ENSPTRP00000009973	Deleted in lymphocytic leukemia 7.	Integral membrane protein 2B; Plays a regulatory role in the processing of the amyloid-beta A4 precursor protein (APP) and acts as an inhibitor of the amyloid-beta peptide aggregation and fibrils deposition. Plays a role in the induction of neurite outgrowth. Functions as a protease inhibitor by blocking access of secretases to APP cleavage sites (By similarity). Bri23 peptide prevents aggregation of APP amyloid-beta protein 42 into toxic oligomers; Belongs to the ITM2 family.	0.562
EBPL	ATP6V0D1	ENSPTRP00000053511	ENSPTRP00000014055	Emopamil binding protein-like.	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family.	0.464
EBPL	DHCR24	ENSPTRP00000053511	ENSPTRP00000001349	Emopamil binding protein-like.	24-dehydrocholesterol reductase.	0.484
EBPL	DLEU7	ENSPTRP00000053511	ENSPTRP00000088785	Emopamil binding protein-like.	Deleted in lymphocytic leukemia 7.	0.465
EBPL	FTSJ1	ENSPTRP00000053511	ENSPTRP00000068287	Emopamil binding protein-like.	Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.	0.495
EBPL	ITM2B	ENSPTRP00000053511	ENSPTRP00000009973	Emopamil binding protein-like.	Integral membrane protein 2B; Plays a regulatory role in the processing of the amyloid-beta A4 precursor protein (APP) and acts as an inhibitor of the amyloid-beta peptide aggregation and fibrils deposition. Plays a role in the induction of neurite outgrowth. Functions as a protease inhibitor by blocking access of secretases to APP cleavage sites (By similarity). Bri23 peptide prevents aggregation of APP amyloid-beta protein 42 into toxic oligomers; Belongs to the ITM2 family.	0.466
EBPL	PPP2R3C	ENSPTRP00000053511	ENSPTRP00000010629	Emopamil binding protein-like.	Protein phosphatase 2, regulatory subunit B'', gamma.	0.495
EBPL	SC5D	ENSPTRP00000053511	ENSPTRP00000066518	Emopamil binding protein-like.	Sterol-C5-desaturase; Belongs to the sterol desaturase family.	0.480
EBPL	TBC1D25	ENSPTRP00000053511	ENSPTRP00000089798	Emopamil binding protein-like.	TBC1 domain family, member 25.	0.495
EBPL	TMEM158	ENSPTRP00000053511	ENSPTRP00000060376	Emopamil binding protein-like.	Transmembrane protein 158.	0.495
EBPL	TSR3	ENSPTRP00000053511	ENSPTRP00000012975	Emopamil binding protein-like.	Probable ribosome biogenesis protein C16orf42 homolog; Probable pre-rRNA processing protein involved in ribosome biogenesis.	0.497
FTSJ1	EBPL	ENSPTRP00000068287	ENSPTRP00000053511	Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.	Emopamil binding protein-like.	0.495
FTSJ1	TBC1D25	ENSPTRP00000068287	ENSPTRP00000089798	Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.	TBC1 domain family, member 25.	0.612
ITM2B	DLEU7	ENSPTRP00000009973	ENSPTRP00000088785	Integral membrane protein 2B; Plays a regulatory role in the processing of the amyloid-beta A4 precursor protein (APP) and acts as an inhibitor of the amyloid-beta peptide aggregation and fibrils deposition. Plays a role in the induction of neurite outgrowth. Functions as a protease inhibitor by blocking access of secretases to APP cleavage sites (By similarity). Bri23 peptide prevents aggregation of APP amyloid-beta protein 42 into toxic oligomers; Belongs to the ITM2 family.	Deleted in lymphocytic leukemia 7.	0.562
ITM2B	EBPL	ENSPTRP00000009973	ENSPTRP00000053511	Integral membrane protein 2B; Plays a regulatory role in the processing of the amyloid-beta A4 precursor protein (APP) and acts as an inhibitor of the amyloid-beta peptide aggregation and fibrils deposition. Plays a role in the induction of neurite outgrowth. Functions as a protease inhibitor by blocking access of secretases to APP cleavage sites (By similarity). Bri23 peptide prevents aggregation of APP amyloid-beta protein 42 into toxic oligomers; Belongs to the ITM2 family.	Emopamil binding protein-like.	0.466
PPP2R3C	EBPL	ENSPTRP00000010629	ENSPTRP00000053511	Protein phosphatase 2, regulatory subunit B'', gamma.	Emopamil binding protein-like.	0.495