| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CDC45 | GINS1 | ENSPTRP00000024215 | ENSPTRP00000088753 | CDC45 isoform 5. | GINS complex subunit 1 (Psf1 homolog). | 0.970 |
| CDC45 | GINS2 | ENSPTRP00000024215 | ENSPTRP00000014382 | CDC45 isoform 5. | DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. | 0.993 |
| CDC45 | GINS3 | ENSPTRP00000024215 | ENSPTRP00000078810 | CDC45 isoform 5. | GINS complex subunit 3. | 0.952 |
| CDC45 | GINS4 | ENSPTRP00000024215 | ENSPTRP00000082269 | CDC45 isoform 5. | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. | 0.970 |
| CDC45 | MCM2 | ENSPTRP00000024215 | ENSPTRP00000026448 | CDC45 isoform 5. | DNA helicase; Belongs to the MCM family. | 0.997 |
| CDC45 | MCM5 | ENSPTRP00000024215 | ENSPTRP00000024625 | CDC45 isoform 5. | DNA helicase; Belongs to the MCM family. | 0.992 |
| CDC45 | MCM6 | ENSPTRP00000024215 | ENSPTRP00000082539 | CDC45 isoform 5. | DNA helicase; Belongs to the MCM family. | 0.996 |
| CDC45 | MCM7 | ENSPTRP00000024215 | ENSPTRP00000033323 | CDC45 isoform 5. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.994 |
| CDC45 | TIMELESS | ENSPTRP00000024215 | ENSPTRP00000042163 | CDC45 isoform 5. | Timeless circadian regulator. | 0.890 |
| CDC45 | TIPIN | ENSPTRP00000024215 | ENSPTRP00000012301 | CDC45 isoform 5. | TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. | 0.758 |
| GINS1 | CDC45 | ENSPTRP00000088753 | ENSPTRP00000024215 | GINS complex subunit 1 (Psf1 homolog). | CDC45 isoform 5. | 0.970 |
| GINS1 | GINS2 | ENSPTRP00000088753 | ENSPTRP00000014382 | GINS complex subunit 1 (Psf1 homolog). | DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. | 0.999 |
| GINS1 | GINS3 | ENSPTRP00000088753 | ENSPTRP00000078810 | GINS complex subunit 1 (Psf1 homolog). | GINS complex subunit 3. | 0.998 |
| GINS1 | GINS4 | ENSPTRP00000088753 | ENSPTRP00000082269 | GINS complex subunit 1 (Psf1 homolog). | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. | 0.999 |
| GINS1 | MCM2 | ENSPTRP00000088753 | ENSPTRP00000026448 | GINS complex subunit 1 (Psf1 homolog). | DNA helicase; Belongs to the MCM family. | 0.950 |
| GINS1 | MCM5 | ENSPTRP00000088753 | ENSPTRP00000024625 | GINS complex subunit 1 (Psf1 homolog). | DNA helicase; Belongs to the MCM family. | 0.958 |
| GINS1 | MCM6 | ENSPTRP00000088753 | ENSPTRP00000082539 | GINS complex subunit 1 (Psf1 homolog). | DNA helicase; Belongs to the MCM family. | 0.945 |
| GINS1 | MCM7 | ENSPTRP00000088753 | ENSPTRP00000033323 | GINS complex subunit 1 (Psf1 homolog). | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.941 |
| GINS1 | TIMELESS | ENSPTRP00000088753 | ENSPTRP00000042163 | GINS complex subunit 1 (Psf1 homolog). | Timeless circadian regulator. | 0.799 |
| GINS1 | TIPIN | ENSPTRP00000088753 | ENSPTRP00000012301 | GINS complex subunit 1 (Psf1 homolog). | TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. | 0.930 |
