TPTE2 protein (Pan troglodytes) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPTRP00000083257	STUB1	ENSPTRP00000083257	ENSPTRP00000012898	annotation not available	STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase.	0.446
ENSPTRP00000083257	TP53	ENSPTRP00000083257	ENSPTRP00000014836	annotation not available	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.903
ENSPTRP00000083257	TPTE2	ENSPTRP00000083257	ENSPTRP00000053686	annotation not available	TPTE isoform 2.	0.721
ENSPTRP00000083257	USP13	ENSPTRP00000083257	ENSPTRP00000026932	annotation not available	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.	0.558
FRK	TPTE2	ENSPTRP00000031633	ENSPTRP00000053686	Tyrosine-protein kinase.	TPTE isoform 2.	0.680
NEDD4	TP53	ENSPTRP00000085467	ENSPTRP00000014836	NEDD4 E3 ubiquitin protein ligase.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.504
NEDD4	TPTE2	ENSPTRP00000085467	ENSPTRP00000053686	NEDD4 E3 ubiquitin protein ligase.	TPTE isoform 2.	0.739
OTUD3	TPTE2	ENSPTRP00000000483	ENSPTRP00000053686	OTU domain containing 3.	TPTE isoform 2.	0.730
SPRTN	TPTE2	ENSPTRP00000003564	ENSPTRP00000053686	SprT-like N-terminal domain.	TPTE isoform 2.	0.830
STUB1	ENSPTRP00000083257	ENSPTRP00000012898	ENSPTRP00000083257	STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase.	annotation not available	0.446
STUB1	TP53	ENSPTRP00000012898	ENSPTRP00000014836	STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.943
STUB1	TPTE2	ENSPTRP00000012898	ENSPTRP00000053686	STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase.	TPTE isoform 2.	0.725
STUB1	USP7	ENSPTRP00000012898	ENSPTRP00000075972	STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase.	Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family.	0.482
TP53	ENSPTRP00000083257	ENSPTRP00000014836	ENSPTRP00000083257	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	annotation not available	0.903
TP53	NEDD4	ENSPTRP00000014836	ENSPTRP00000085467	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	NEDD4 E3 ubiquitin protein ligase.	0.504
TP53	STUB1	ENSPTRP00000014836	ENSPTRP00000012898	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase.	0.943
TP53	TPTE2	ENSPTRP00000014836	ENSPTRP00000053686	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	TPTE isoform 2.	0.802
TP53	USP7	ENSPTRP00000014836	ENSPTRP00000075972	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family.	0.997
TP53	WWP2	ENSPTRP00000014836	ENSPTRP00000070966	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	E3 ubiquitin-protein ligase.	0.554
TPTE2	ENSPTRP00000083257	ENSPTRP00000053686	ENSPTRP00000083257	TPTE isoform 2.	annotation not available	0.721