TPTE2 protein (Pan troglodytes) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

TPTE2

TPTE isoform 2. (539 aa)

Predicted Functional Partners:

SPRTN

0.777

NEDD4

0.614

USP7

0.611

ENSPTRP00000083257

0.611

GAK

0.603

WWP2

0.586

MTMR2

0.574

TP53

0.568

STUB1

0.548

OTUD3

0.543

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPTRP00000083257	NEDD4	ENSPTRP00000083257	ENSPTRP00000085467	annotation not available	NEDD4 E3 ubiquitin protein ligase.	0.534
ENSPTRP00000083257	TP53	ENSPTRP00000083257	ENSPTRP00000014836	annotation not available	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.961
ENSPTRP00000083257	TPTE2	ENSPTRP00000083257	ENSPTRP00000053686	annotation not available	TPTE isoform 2.	0.611
GAK	SPRTN	ENSPTRP00000091059	ENSPTRP00000003564	Cyclin G associated kinase.	SprT-like N-terminal domain.	0.650
GAK	TPTE2	ENSPTRP00000091059	ENSPTRP00000053686	Cyclin G associated kinase.	TPTE isoform 2.	0.603
GAK	WWP2	ENSPTRP00000091059	ENSPTRP00000070966	Cyclin G associated kinase.	E3 ubiquitin-protein ligase.	0.443
MTMR2	TPTE2	ENSPTRP00000046198	ENSPTRP00000053686	MTMR2 isoform 3.	TPTE isoform 2.	0.574
NEDD4	ENSPTRP00000083257	ENSPTRP00000085467	ENSPTRP00000083257	NEDD4 E3 ubiquitin protein ligase.	annotation not available	0.534
NEDD4	STUB1	ENSPTRP00000085467	ENSPTRP00000012898	NEDD4 E3 ubiquitin protein ligase.	STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase.	0.441
NEDD4	TP53	ENSPTRP00000085467	ENSPTRP00000014836	NEDD4 E3 ubiquitin protein ligase.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.619
NEDD4	TPTE2	ENSPTRP00000085467	ENSPTRP00000053686	NEDD4 E3 ubiquitin protein ligase.	TPTE isoform 2.	0.614
NEDD4	USP7	ENSPTRP00000085467	ENSPTRP00000075972	NEDD4 E3 ubiquitin protein ligase.	Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family.	0.571
OTUD3	TPTE2	ENSPTRP00000000483	ENSPTRP00000053686	OTU domain containing 3.	TPTE isoform 2.	0.543
SPRTN	GAK	ENSPTRP00000003564	ENSPTRP00000091059	SprT-like N-terminal domain.	Cyclin G associated kinase.	0.650
SPRTN	TPTE2	ENSPTRP00000003564	ENSPTRP00000053686	SprT-like N-terminal domain.	TPTE isoform 2.	0.777
STUB1	NEDD4	ENSPTRP00000012898	ENSPTRP00000085467	STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase.	NEDD4 E3 ubiquitin protein ligase.	0.441
STUB1	TP53	ENSPTRP00000012898	ENSPTRP00000014836	STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.918
STUB1	TPTE2	ENSPTRP00000012898	ENSPTRP00000053686	STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase.	TPTE isoform 2.	0.548
TP53	ENSPTRP00000083257	ENSPTRP00000014836	ENSPTRP00000083257	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	annotation not available	0.961
TP53	NEDD4	ENSPTRP00000014836	ENSPTRP00000085467	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	NEDD4 E3 ubiquitin protein ligase.	0.619