| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BIVM | ERCC1 | ENSPTRP00000053370 | ENSPTRP00000076815 | BIVM-ERCC5 isoform 1. | ERCC excision repair 1, endonuclease non-catalytic subunit. | 0.932 |
| BIVM | ERCC2 | ENSPTRP00000053370 | ENSPTRP00000079029 | BIVM-ERCC5 isoform 1. | ERCC excision repair 2, TFIIH core complex helicase subunit. | 0.963 |
| BIVM | ERCC3 | ENSPTRP00000053370 | ENSPTRP00000087351 | BIVM-ERCC5 isoform 1. | ERCC excision repair 3, TFIIH core complex helicase subunit. | 0.975 |
| BIVM | ERCC4 | ENSPTRP00000053370 | ENSPTRP00000053757 | BIVM-ERCC5 isoform 1. | Excision repair cross-complementing rodent repair deficiency, complementation group 4. | 0.956 |
| BIVM | MUS81 | ENSPTRP00000053370 | ENSPTRP00000006717 | BIVM-ERCC5 isoform 1. | MUS81 structure-specific endonuclease subunit. | 0.900 |
| BIVM | RAD51 | ENSPTRP00000053370 | ENSPTRP00000068995 | BIVM-ERCC5 isoform 1. | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] | 0.779 |
| BIVM | SLX1A | ENSPTRP00000053370 | ENSPTRP00000058845 | BIVM-ERCC5 isoform 1. | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. | 0.618 |
| BIVM | SLX4 | ENSPTRP00000053370 | ENSPTRP00000013163 | BIVM-ERCC5 isoform 1. | SLX4 structure-specific endonuclease subunit. | 0.485 |
| BIVM | XPA | ENSPTRP00000053370 | ENSPTRP00000036174 | BIVM-ERCC5 isoform 1. | Xeroderma pigmentosum, complementation group A. | 0.987 |
| BIVM | XPC | ENSPTRP00000053370 | ENSPTRP00000051558 | BIVM-ERCC5 isoform 1. | XPC complex subunit, DNA damage recognition and repair factor. | 0.889 |
| ERCC1 | BIVM | ENSPTRP00000076815 | ENSPTRP00000053370 | ERCC excision repair 1, endonuclease non-catalytic subunit. | BIVM-ERCC5 isoform 1. | 0.932 |
| ERCC1 | ERCC2 | ENSPTRP00000076815 | ENSPTRP00000079029 | ERCC excision repair 1, endonuclease non-catalytic subunit. | ERCC excision repair 2, TFIIH core complex helicase subunit. | 0.939 |
| ERCC1 | ERCC3 | ENSPTRP00000076815 | ENSPTRP00000087351 | ERCC excision repair 1, endonuclease non-catalytic subunit. | ERCC excision repair 3, TFIIH core complex helicase subunit. | 0.954 |
| ERCC1 | ERCC4 | ENSPTRP00000076815 | ENSPTRP00000053757 | ERCC excision repair 1, endonuclease non-catalytic subunit. | Excision repair cross-complementing rodent repair deficiency, complementation group 4. | 0.999 |
| ERCC1 | MUS81 | ENSPTRP00000076815 | ENSPTRP00000006717 | ERCC excision repair 1, endonuclease non-catalytic subunit. | MUS81 structure-specific endonuclease subunit. | 0.981 |
| ERCC1 | RAD51 | ENSPTRP00000076815 | ENSPTRP00000068995 | ERCC excision repair 1, endonuclease non-catalytic subunit. | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] | 0.650 |
| ERCC1 | SLX1A | ENSPTRP00000076815 | ENSPTRP00000058845 | ERCC excision repair 1, endonuclease non-catalytic subunit. | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. | 0.954 |
| ERCC1 | SLX4 | ENSPTRP00000076815 | ENSPTRP00000013163 | ERCC excision repair 1, endonuclease non-catalytic subunit. | SLX4 structure-specific endonuclease subunit. | 0.989 |
| ERCC1 | XPA | ENSPTRP00000076815 | ENSPTRP00000036174 | ERCC excision repair 1, endonuclease non-catalytic subunit. | Xeroderma pigmentosum, complementation group A. | 0.999 |
| ERCC1 | XPC | ENSPTRP00000076815 | ENSPTRP00000051558 | ERCC excision repair 1, endonuclease non-catalytic subunit. | XPC complex subunit, DNA damage recognition and repair factor. | 0.869 |
