STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ITSN1ITSN1 isoform 4. (1721 aa)    
Predicted Functional Partners:
AP2M1
AP2M1 isoform 3; Belongs to the adaptor complexes medium subunit family.
    
 0.975
AP2S1
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
   
 0.975
WASL
WASP like actin nucleation promoting factor.
    
 0.972
FCHO1
FCHO1 isoform 7.
   
 0.971
CDC42
Cell division cycle 42 (GTP binding protein, 25kDa).
    
 0.967
GAS7
Growth arrest-specific 7.
   
 0.961
WAS
WAS isoform 1.
    
 0.955
WAS-2
WASP actin nucleation promoting factor.
    
 0.955
NECAP1
NECAP endocytosis associated 1.
    
 0.950
EPS15
Epidermal growth factor receptor pathway substrate 15.
   
0.948
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.