Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SYNJ1SYNJ1 isoform 6. (1614 aa)    
Predicted Functional Partners:
ITSN1-2
ITSN1 isoform 7.
   
 
 0.907
ITSN1
ITSN1 isoform 4.
   
 
 0.896
SNX9
Sorting nexin.
   
 
 0.858
SH3GL2
SH3 domain containing GRB2 like 2, endophilin A1.
    
 
 0.849
ITSN2
ITSN2 isoform 1.
   
 
 0.843
AMPH
AMPH isoform 1.
   
 
 0.837
AP2M1
AP2M1 isoform 3; Belongs to the adaptor complexes medium subunit family.
    
 
 0.725
BIN1
Bridging integrator 1.
   
 
 0.722
VPS13C
VPS13C isoform 4.
   
 
 0.706
RIC3
RIC3 acetylcholine receptor chaperone.
     
 0.681
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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