STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFF2AF4/FMR2 family member 2; RNA-binding protein. Might be involved in alternative splicing regulation through an interaction with G-quartet RNA structure (By similarity); Belongs to the AF4 family. (1301 aa)    
Predicted Functional Partners:
CYLC1
CYLC1 isoform 2.
   
 0.871
FMR1
Fragile X mental retardation 1.
    
 
 0.840
ARL13A
ADP ribosylation factor like GTPase 13A.
      
 0.833
TEX13A
Testis expressed 13A.
      
 0.713
UNC79
UNC79 isoform 1.
    
 0.675
MAGEB10
MAGE family member B10.
    
 
 0.627
MLLT1
Myeloid/lymphoid or mixed-lineage leukemia translocated to, 1.
   
 0.607
ELL
Elongation factor for RNA polymerase II.
    
 0.597
CDK9
Cyclin-dependent kinase 9; Belongs to the protein kinase superfamily.
    
 0.595
MLLT3
MLLT3 isoform 1.
   
 0.577
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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