CXCR6 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCL25	CCL5	ENSPTRP00000017715	ENSPTRP00000083031	C-C motif chemokine ligand 25.	C-C motif chemokine.	0.931
CCL25	CD4	ENSPTRP00000017715	ENSPTRP00000054833	C-C motif chemokine ligand 25.	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	0.604
CCL25	CXCL10	ENSPTRP00000017715	ENSPTRP00000027807	C-C motif chemokine ligand 25.	C-X-C motif chemokine.	0.760
CCL25	CXCL12	ENSPTRP00000017715	ENSPTRP00000067989	C-C motif chemokine ligand 25.	C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family.	0.967
CCL25	CXCL13	ENSPTRP00000017715	ENSPTRP00000027829	C-C motif chemokine ligand 25.	C-X-C motif chemokine.	0.621
CCL25	CXCL16	ENSPTRP00000017715	ENSPTRP00000014690	C-C motif chemokine ligand 25.	Chemokine (C-X-C motif) ligand 16.	0.676
CCL25	CXCL9	ENSPTRP00000017715	ENSPTRP00000027806	C-C motif chemokine ligand 25.	C-X-C motif chemokine.	0.750
CCL25	CXCR6	ENSPTRP00000017715	ENSPTRP00000054532	C-C motif chemokine ligand 25.	C-X-C chemokine receptor type 6; Receptor for the C-X-C chemokine CXCL16. Used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1.	0.970
CCL5	CCL25	ENSPTRP00000083031	ENSPTRP00000017715	C-C motif chemokine.	C-C motif chemokine ligand 25.	0.931
CCL5	CD4	ENSPTRP00000083031	ENSPTRP00000054833	C-C motif chemokine.	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	0.860
CCL5	CXCL10	ENSPTRP00000083031	ENSPTRP00000027807	C-C motif chemokine.	C-X-C motif chemokine.	0.989
CCL5	CXCL12	ENSPTRP00000083031	ENSPTRP00000067989	C-C motif chemokine.	C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family.	0.958
CCL5	CXCL13	ENSPTRP00000083031	ENSPTRP00000027829	C-C motif chemokine.	C-X-C motif chemokine.	0.750
CCL5	CXCL16	ENSPTRP00000083031	ENSPTRP00000014690	C-C motif chemokine.	Chemokine (C-X-C motif) ligand 16.	0.686
CCL5	CXCL9	ENSPTRP00000083031	ENSPTRP00000027806	C-C motif chemokine.	C-X-C motif chemokine.	0.977
CCL5	CXCR6	ENSPTRP00000083031	ENSPTRP00000054532	C-C motif chemokine.	C-X-C chemokine receptor type 6; Receptor for the C-X-C chemokine CXCL16. Used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1.	0.875
CD4	CCL25	ENSPTRP00000054833	ENSPTRP00000017715	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	C-C motif chemokine ligand 25.	0.604
CD4	CCL5	ENSPTRP00000054833	ENSPTRP00000083031	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	C-C motif chemokine.	0.860
CD4	CXCL10	ENSPTRP00000054833	ENSPTRP00000027807	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	C-X-C motif chemokine.	0.894
CD4	CXCL12	ENSPTRP00000054833	ENSPTRP00000067989	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family.	0.804