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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HLA-APatr class I histocompatibility antigen, A-108 alpha chain; Involved in the presentation of foreign antigens to the immune system. (365 aa)    
Predicted Functional Partners:
B2M
Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).
   
 0.993
TRAC
TRAC isoform 1.
    
  0.949
CK820_G0055106
IGHV3-66 isoform 1.
    
  0.927
IGLL5
IGLL5 isoform 1.
    
  0.905
KIR3DL1
Killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1.
    
 0.840
KIR2DL6-2
KIR2DL4 isoform 7.
    
 0.838
KLRD1
Natural killer cells antigen CD94; Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.
    
 0.831
KIR3DL5
Pan troglodytes killer cell immunoglobulin-like receptor (KIR3DL5), mRNA.
    
 0.826
KIR2DL1
KIR2DL1 isoform 1.
    
 0.812
CALR
Calreticulin.
    
 0.745
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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