GRIN2A protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CALM3	CALML5	ENSPTRP00000019197	ENSPTRP00000003820	Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family.	Calmodulin like 5.	0.932
CALM3	DLG3	ENSPTRP00000019197	ENSPTRP00000069805	Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family.	Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family.	0.593
CALM3	DLG4	ENSPTRP00000019197	ENSPTRP00000014780	Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family.	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	0.728
CALM3	GRIN1	ENSPTRP00000019197	ENSPTRP00000041565	Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family.	Glutamate receptor, ionotropic, N-methyl D-aspartate 1.	0.976
CALM3	GRIN2A	ENSPTRP00000019197	ENSPTRP00000055315	Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family.	Glutamate receptor ionotropic, NMDA 2A; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition; channels containing GRIN1 and GRIN2A have higher sensitivity to glutamate and faster kineti [...]	0.974
CALM3	GRIN2B	ENSPTRP00000019197	ENSPTRP00000008060	Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family.	Glutamate ionotropic receptor NMDA type subunit 2B.	0.948
CALM3	GRIN2C	ENSPTRP00000019197	ENSPTRP00000072438	Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family.	GRIN2C isoform 4.	0.930
CALM3	NOS1	ENSPTRP00000019197	ENSPTRP00000092025	Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family.	Nitric oxide synthase 1.	0.980
CALML5	CALM3	ENSPTRP00000003820	ENSPTRP00000019197	Calmodulin like 5.	Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family.	0.932
CALML5	DLG3	ENSPTRP00000003820	ENSPTRP00000069805	Calmodulin like 5.	Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family.	0.530
CALML5	DLG4	ENSPTRP00000003820	ENSPTRP00000014780	Calmodulin like 5.	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	0.712
CALML5	GRIN1	ENSPTRP00000003820	ENSPTRP00000041565	Calmodulin like 5.	Glutamate receptor, ionotropic, N-methyl D-aspartate 1.	0.960
CALML5	GRIN2A	ENSPTRP00000003820	ENSPTRP00000055315	Calmodulin like 5.	Glutamate receptor ionotropic, NMDA 2A; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition; channels containing GRIN1 and GRIN2A have higher sensitivity to glutamate and faster kineti [...]	0.954
CALML5	GRIN2B	ENSPTRP00000003820	ENSPTRP00000008060	Calmodulin like 5.	Glutamate ionotropic receptor NMDA type subunit 2B.	0.958
CALML5	GRIN2C	ENSPTRP00000003820	ENSPTRP00000072438	Calmodulin like 5.	GRIN2C isoform 4.	0.926
CALML5	NOS1	ENSPTRP00000003820	ENSPTRP00000092025	Calmodulin like 5.	Nitric oxide synthase 1.	0.971
DLG3	CALM3	ENSPTRP00000069805	ENSPTRP00000019197	Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family.	Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family.	0.593
DLG3	CALML5	ENSPTRP00000069805	ENSPTRP00000003820	Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family.	Calmodulin like 5.	0.530
DLG3	DLG4	ENSPTRP00000069805	ENSPTRP00000014780	Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family.	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	0.992
DLG3	GRIN1	ENSPTRP00000069805	ENSPTRP00000041565	Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family.	Glutamate receptor, ionotropic, N-methyl D-aspartate 1.	0.922