STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPAG11BSperm-associated antigen 11; Belongs to the SPAG11 family. (113 aa)    
Predicted Functional Partners:
DEFB107A
Beta-defensin 107A; Has antibacterial activity; Belongs to the beta-defensin family.
      
 0.843
DEFB106A
Beta-defensin 106A; Has antibacterial activity. Acts as a ligand for C-C chemokine receptor CCR2.
      
 0.831
DEFB105A
Beta-defensin 105A; Has antimicrobial activity; Belongs to the beta-defensin family.
      
 0.830
DEFB104
Beta-defensin 104A; Has antimicrobial activity; Belongs to the beta-defensin family.
      
 0.778
DEFB103A
Beta-defensin 103A; Exhibits antimicrobial activity against Gram-positive and Gram-negative bacteria; Belongs to the beta-defensin family.
      
 0.760
PRR23C
PRR23C isoform 1.
      
 0.656
PRR23A
PRR23A isoform 1.
      
 0.656
PRR23B
PRR23B isoform 1.
      
 0.621
IARS1
Isoleucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
      
 0.620
DEFB130
Beta-defensin 130; Antimicrobial host-defense peptide. Belongs to the beta-defensin family.
  
   
 0.614
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.