KIR2DL3 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADGRL3	KIR2DL3	ENSPTRP00000078995	ENSPTRP00000056184	Adhesion G protein-coupled receptor L3; Belongs to the G-protein coupled receptor 2 family.	KIR2DL3 isoform 1.	0.548
ENSPTRP00000079788	KIR2DL3	ENSPTRP00000079788	ENSPTRP00000056184	annotation not available	KIR2DL3 isoform 1.	0.534
ENSPTRP00000079788	KIR3DL1-2	ENSPTRP00000079788	ENSPTRP00000056827	annotation not available	KIR3DL1 isoform 2.	0.662
ENSPTRP00000079788	KIR3DL3	ENSPTRP00000079788	ENSPTRP00000057863	annotation not available	KIR3DL3 isoform 1.	0.630
ENSPTRP00000079788	PATR-AL	ENSPTRP00000079788	ENSPTRP00000068372	annotation not available	Major histocompatibility complex, class I, AL precursor.	0.456
HLA-A	KIR2DL3	ENSPTRP00000089515	ENSPTRP00000056184	Patr class I histocompatibility antigen, A-108 alpha chain; Involved in the presentation of foreign antigens to the immune system.	KIR2DL3 isoform 1.	0.687
HLA-A	KIR2DL4	ENSPTRP00000089515	ENSPTRP00000072750	Patr class I histocompatibility antigen, A-108 alpha chain; Involved in the presentation of foreign antigens to the immune system.	KIR2DL4 isoform 5.	0.577
HLA-A	KIR3DL1-2	ENSPTRP00000089515	ENSPTRP00000056827	Patr class I histocompatibility antigen, A-108 alpha chain; Involved in the presentation of foreign antigens to the immune system.	KIR3DL1 isoform 2.	0.781
HLA-A	KIR3DL3	ENSPTRP00000089515	ENSPTRP00000057863	Patr class I histocompatibility antigen, A-108 alpha chain; Involved in the presentation of foreign antigens to the immune system.	KIR3DL3 isoform 1.	0.609
HLA-A	KLRD1	ENSPTRP00000089515	ENSPTRP00000057110	Patr class I histocompatibility antigen, A-108 alpha chain; Involved in the presentation of foreign antigens to the immune system.	Natural killer cells antigen CD94; Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.	0.951
HLA-A	TYROBP	ENSPTRP00000089515	ENSPTRP00000018632	Patr class I histocompatibility antigen, A-108 alpha chain; Involved in the presentation of foreign antigens to the immune system.	TYRO protein tyrosine kinase-binding protein; Adapter protein which non-covalently associates with activating receptors found on the surface of a variety of immune cells to mediate signaling and cell activation following ligand binding by the receptors (By similarity). TYROBP is tyrosine-phosphorylated in the ITAM domain following ligand binding by the associated receptors which leads to activation of additional tyrosine kinases and subsequent cell activation (By similarity). Also has an inhibitory role in some cells (By similarity). Non-covalently associates with activating receptors [...]	0.502
KIR2DL3	ADGRL3	ENSPTRP00000056184	ENSPTRP00000078995	KIR2DL3 isoform 1.	Adhesion G protein-coupled receptor L3; Belongs to the G-protein coupled receptor 2 family.	0.548
KIR2DL3	ENSPTRP00000079788	ENSPTRP00000056184	ENSPTRP00000079788	KIR2DL3 isoform 1.	annotation not available	0.534
KIR2DL3	HLA-A	ENSPTRP00000056184	ENSPTRP00000089515	KIR2DL3 isoform 1.	Patr class I histocompatibility antigen, A-108 alpha chain; Involved in the presentation of foreign antigens to the immune system.	0.687
KIR2DL3	KIR2DL4	ENSPTRP00000056184	ENSPTRP00000072750	KIR2DL3 isoform 1.	KIR2DL4 isoform 5.	0.534
KIR2DL3	KIR3DL1-2	ENSPTRP00000056184	ENSPTRP00000056827	KIR2DL3 isoform 1.	KIR3DL1 isoform 2.	0.784
KIR2DL3	KIR3DL3	ENSPTRP00000056184	ENSPTRP00000057863	KIR2DL3 isoform 1.	KIR3DL3 isoform 1.	0.721
KIR2DL3	KLRD1	ENSPTRP00000056184	ENSPTRP00000057110	KIR2DL3 isoform 1.	Natural killer cells antigen CD94; Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.	0.654
KIR2DL3	LOC107969810	ENSPTRP00000056184	ENSPTRP00000048489	KIR2DL3 isoform 1.	LOW QUALITY PROTEIN: killer cell immunoglobulin-like receptor 2DL5A.	0.534
KIR2DL3	PATR-AL	ENSPTRP00000056184	ENSPTRP00000068372	KIR2DL3 isoform 1.	Major histocompatibility complex, class I, AL precursor.	0.649