P2RY4 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADA2	P2RX1	ENSPTRP00000049871	ENSPTRP00000014652	Adenosine deaminase 2.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.429
ADA2	P2RY4	ENSPTRP00000049871	ENSPTRP00000057506	Adenosine deaminase 2.	Pyrimidinergic receptor P2Y4; Belongs to the G-protein coupled receptor 1 family.	0.525
GNA11	GNAQ	ENSPTRP00000074292	ENSPTRP00000049267	Guanine nucleotide binding protein (G protein), alpha 11 (Gq class).	Guanine nucleotide binding protein (G protein), q polypeptide.	0.997
GNA11	GNB1	ENSPTRP00000074292	ENSPTRP00000067330	Guanine nucleotide binding protein (G protein), alpha 11 (Gq class).	Guanine nucleotide binding protein (G protein), beta polypeptide 1.	0.922
GNA11	GNG2	ENSPTRP00000074292	ENSPTRP00000065345	Guanine nucleotide binding protein (G protein), alpha 11 (Gq class).	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.804
GNA11	P2RY4	ENSPTRP00000074292	ENSPTRP00000057506	Guanine nucleotide binding protein (G protein), alpha 11 (Gq class).	Pyrimidinergic receptor P2Y4; Belongs to the G-protein coupled receptor 1 family.	0.905
GNAQ	GNA11	ENSPTRP00000049267	ENSPTRP00000074292	Guanine nucleotide binding protein (G protein), q polypeptide.	Guanine nucleotide binding protein (G protein), alpha 11 (Gq class).	0.997
GNAQ	GNB1	ENSPTRP00000049267	ENSPTRP00000067330	Guanine nucleotide binding protein (G protein), q polypeptide.	Guanine nucleotide binding protein (G protein), beta polypeptide 1.	0.990
GNAQ	GNG2	ENSPTRP00000049267	ENSPTRP00000065345	Guanine nucleotide binding protein (G protein), q polypeptide.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.974
GNAQ	P2RY4	ENSPTRP00000049267	ENSPTRP00000057506	Guanine nucleotide binding protein (G protein), q polypeptide.	Pyrimidinergic receptor P2Y4; Belongs to the G-protein coupled receptor 1 family.	0.910
GNB1	GNA11	ENSPTRP00000067330	ENSPTRP00000074292	Guanine nucleotide binding protein (G protein), beta polypeptide 1.	Guanine nucleotide binding protein (G protein), alpha 11 (Gq class).	0.922
GNB1	GNAQ	ENSPTRP00000067330	ENSPTRP00000049267	Guanine nucleotide binding protein (G protein), beta polypeptide 1.	Guanine nucleotide binding protein (G protein), q polypeptide.	0.990
GNB1	GNG2	ENSPTRP00000067330	ENSPTRP00000065345	Guanine nucleotide binding protein (G protein), beta polypeptide 1.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.999
GNB1	P2RY4	ENSPTRP00000067330	ENSPTRP00000057506	Guanine nucleotide binding protein (G protein), beta polypeptide 1.	Pyrimidinergic receptor P2Y4; Belongs to the G-protein coupled receptor 1 family.	0.564
GNG2	GNA11	ENSPTRP00000065345	ENSPTRP00000074292	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Guanine nucleotide binding protein (G protein), alpha 11 (Gq class).	0.804
GNG2	GNAQ	ENSPTRP00000065345	ENSPTRP00000049267	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Guanine nucleotide binding protein (G protein), q polypeptide.	0.974
GNG2	GNB1	ENSPTRP00000065345	ENSPTRP00000067330	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Guanine nucleotide binding protein (G protein), beta polypeptide 1.	0.999
GNG2	P2RY4	ENSPTRP00000065345	ENSPTRP00000057506	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Pyrimidinergic receptor P2Y4; Belongs to the G-protein coupled receptor 1 family.	0.573
NTRK3	P2RY4	ENSPTRP00000085547	ENSPTRP00000057506	NT-3 growth factor receptor; Receptor tyrosine kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling pathways, including the phosphatidylinositol 3-kinase/AKT and the MAPK pathways, that control cell survival and differentiation.	Pyrimidinergic receptor P2Y4; Belongs to the G-protein coupled receptor 1 family.	0.496
P2RX1	ADA2	ENSPTRP00000014652	ENSPTRP00000049871	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	Adenosine deaminase 2.	0.429