STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TCF3TCF3 isoform 3. (673 aa)    
Predicted Functional Partners:
TAL1
TAL bHLH transcription factor 1, erythroid differentiation factor.
   
 0.985
MYOD1
Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.
   
 0.955
MYOG
MYOG isoform 1.
   
 0.934
LMO2
LIM domain only 2.
    
 0.933
LDB2
LIM domain binding 2.
   
 0.919
GATA1
GATA binding protein 1.
   
 0.886
CREBBP
CREB binding protein.
    
 0.885
ID3
Inhibitor of DNA binding 3, dominant negative helix-loop-helix protein.
    
 
 0.882
ID2
Inhibitor of DNA binding 2, dominant negative helix-loop-helix protein.
    
 
 0.876
ENSPTRP00000084126
annotation not available
    
 
 0.876
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.