TCF3 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CREBBP	EP300	ENSPTRP00000074980	ENSPTRP00000024841	CREB binding protein.	E1A binding protein p300.	0.999
CREBBP	MYOD1	ENSPTRP00000074980	ENSPTRP00000005943	CREB binding protein.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.844
CREBBP	MYOG	ENSPTRP00000074980	ENSPTRP00000044084	CREB binding protein.	MYOG isoform 1.	0.422
CREBBP	TAL1	ENSPTRP00000074980	ENSPTRP00000063843	CREB binding protein.	TAL bHLH transcription factor 1, erythroid differentiation factor.	0.598
CREBBP	TCF3	ENSPTRP00000074980	ENSPTRP00000067488	CREB binding protein.	TCF3 isoform 3.	0.938
CREBBP	TCF4	ENSPTRP00000074980	ENSPTRP00000040814	CREB binding protein.	Transcription factor 4.	0.783
EP300	CREBBP	ENSPTRP00000024841	ENSPTRP00000074980	E1A binding protein p300.	CREB binding protein.	0.999
EP300	MYOD1	ENSPTRP00000024841	ENSPTRP00000005943	E1A binding protein p300.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.943
EP300	MYOG	ENSPTRP00000024841	ENSPTRP00000044084	E1A binding protein p300.	MYOG isoform 1.	0.521
EP300	TAL1	ENSPTRP00000024841	ENSPTRP00000063843	E1A binding protein p300.	TAL bHLH transcription factor 1, erythroid differentiation factor.	0.775
EP300	TCF3	ENSPTRP00000024841	ENSPTRP00000067488	E1A binding protein p300.	TCF3 isoform 3.	0.874
EP300	TCF4	ENSPTRP00000024841	ENSPTRP00000040814	E1A binding protein p300.	Transcription factor 4.	0.709
EP300	TWIST1	ENSPTRP00000024841	ENSPTRP00000048124	E1A binding protein p300.	TWIST1 isoform 2.	0.617
ID1	ID1-2	ENSPTRP00000059507	ENSPTRP00000085515	Inhibitor of DNA binding 1, dominant negative helix-loop-helix protein.	Inhibitor of DNA binding 1, HLH protein.	0.801
ID1	ID3	ENSPTRP00000059507	ENSPTRP00000000580	Inhibitor of DNA binding 1, dominant negative helix-loop-helix protein.	Inhibitor of DNA binding 3, dominant negative helix-loop-helix protein.	0.628
ID1	MYOD1	ENSPTRP00000059507	ENSPTRP00000005943	Inhibitor of DNA binding 1, dominant negative helix-loop-helix protein.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.818
ID1	MYOG	ENSPTRP00000059507	ENSPTRP00000044084	Inhibitor of DNA binding 1, dominant negative helix-loop-helix protein.	MYOG isoform 1.	0.561
ID1	TCF3	ENSPTRP00000059507	ENSPTRP00000067488	Inhibitor of DNA binding 1, dominant negative helix-loop-helix protein.	TCF3 isoform 3.	0.984
ID1	TCF4	ENSPTRP00000059507	ENSPTRP00000040814	Inhibitor of DNA binding 1, dominant negative helix-loop-helix protein.	Transcription factor 4.	0.816
ID1-2	ID1	ENSPTRP00000085515	ENSPTRP00000059507	Inhibitor of DNA binding 1, HLH protein.	Inhibitor of DNA binding 1, dominant negative helix-loop-helix protein.	0.801