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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CALML4Calmodulin like 4. (196 aa)    
Predicted Functional Partners:
NOS3
Nitric oxide synthase; Produces nitric oxide (NO).
    
 0.892
CAMK2A
Calcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily.
    
 0.891
MARCKS
Myristoylated alanine-rich protein kinase C substrate.
    
 0.887
NOS1
Nitric oxide synthase 1.
    
 0.886
IQGAP1
IQ motif containing GTPase activating protein 1.
    
 0.883
RYR2
RYR2 isoform 1.
    
 
 0.872
MYLK2
MYLK2 isoform 1.
   
 0.867
NRGN
NRGN isoform 1.
    
 0.857
KCNQ1
Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family.
    
 0.845
PPP3CA
Serine/threonine-protein phosphatase.
    
 0.844
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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