Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TBPTBP isoform 1. (336 aa)    
Predicted Functional Partners:
GTF2B
General transcription factor IIB.
   
 0.999
TAF1
Transcription initiation factor TFIID subunit.
    
 0.994
TAF2
TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa.
    
 0.992
TAF3
TATA-box binding protein associated factor 3.
    
 0.991
TBPL2
TATA box-binding protein-like protein 2; Transcription factor required in complex with TAF3 for the differentiation of myoblasts into myocytes. The complex replaces TFIID at specific promoters at an early stage in the differentiation process (By similarity).
  
 
 
0.991
TAF6
TATA-box binding protein associated factor 6.
   
 0.991
TAF12
TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa.
    
 0.990
TAF10
Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family.
    
 0.990
TAF5
TATA-box binding protein associated factor 5.
   
 0.990
TAF8
TATA-box binding protein associated factor 8.
   
 0.990
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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