| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| COMT | CYP1A1 | ENSPTRP00000024231 | ENSPTRP00000058539 | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | 0.952 |
| COMT | UGT1A3 | ENSPTRP00000024231 | ENSPTRP00000082441 | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. | UDP-glucuronosyltransferase 1-3 isoform X2. | 0.938 |
| COMT | UGT1A5 | ENSPTRP00000024231 | ENSPTRP00000063403 | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. | 0.938 |
| CYP19A1 | CYP1A1 | ENSPTRP00000012092 | ENSPTRP00000058539 | Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | 0.948 |
| CYP19A1 | CYP3A4 | ENSPTRP00000012092 | ENSPTRP00000081767 | Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 family 3 subfamily A member 4. | 0.937 |
| CYP19A1 | CYP3A5 | ENSPTRP00000012092 | ENSPTRP00000033296 | Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family. | CYP3A5 isoform 1. | 0.936 |
| CYP19A1 | CYP7A1 | ENSPTRP00000012092 | ENSPTRP00000034711 | Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family. | Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. | 0.708 |
| CYP19A1 | UGT1A3 | ENSPTRP00000012092 | ENSPTRP00000082441 | Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family. | UDP-glucuronosyltransferase 1-3 isoform X2. | 0.925 |
| CYP19A1 | UGT1A5 | ENSPTRP00000012092 | ENSPTRP00000063403 | Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family. | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. | 0.925 |
| CYP1A1 | COMT | ENSPTRP00000058539 | ENSPTRP00000024231 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. | 0.952 |
| CYP1A1 | CYP19A1 | ENSPTRP00000058539 | ENSPTRP00000012092 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family. | 0.948 |
| CYP1A1 | CYP3A4 | ENSPTRP00000058539 | ENSPTRP00000081767 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 family 3 subfamily A member 4. | 0.958 |
| CYP1A1 | CYP3A5 | ENSPTRP00000058539 | ENSPTRP00000033296 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | CYP3A5 isoform 1. | 0.952 |
| CYP1A1 | CYP3A7 | ENSPTRP00000058539 | ENSPTRP00000090746 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Cytochrome P450, family 3, subfamily A, polypeptide 67. | 0.951 |
| CYP1A1 | CYP3A7-2 | ENSPTRP00000058539 | ENSPTRP00000064878 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | CYP3A7 isoform 2. | 0.951 |
| CYP1A1 | CYP7A1 | ENSPTRP00000058539 | ENSPTRP00000034711 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. | 0.962 |
| CYP1A1 | EPHX1 | ENSPTRP00000058539 | ENSPTRP00000003444 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Epoxide hydrolase; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Belongs to the peptidase S33 family. | 0.949 |
| CYP1A1 | UGT1A3 | ENSPTRP00000058539 | ENSPTRP00000082441 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | UDP-glucuronosyltransferase 1-3 isoform X2. | 0.949 |
| CYP1A1 | UGT1A5 | ENSPTRP00000058539 | ENSPTRP00000063403 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. | 0.949 |
| CYP3A4 | CYP19A1 | ENSPTRP00000081767 | ENSPTRP00000012092 | Cytochrome P450 family 3 subfamily A member 4. | Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family. | 0.937 |
