STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TGM5Transglutaminase 5. (720 aa)    
Predicted Functional Partners:
RXFP4
Relaxin family peptide/INSL5 receptor 4.
      
 0.832
ACP4
ACP4 isoform 1; Belongs to the histidine acid phosphatase family.
      
 0.830
ACOX2
Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.
    
 
 0.803
KLK8
Kallikrein related peptidase 8; Belongs to the peptidase S1 family.
     
 0.796
AMTN
AMTN isoform 1.
      
 0.765
DSG4
DSG4 isoform 2; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
    
 0.741
ABCB4
ABCB4 isoform 4.
   
  
 0.730
CDSN
Corneodesmosin; Important for the epidermal barrier integrity.
   
 
 0.702
ENAM
ENAM isoform 1.
      
 0.701
GNAT2
G protein subunit alpha transducin 2.
    
 
 0.593
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.