| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ATG3 | ATG5 | ENSPTRP00000026253 | ENSPTRP00000031526 | Autophagy-related protein 3. | Autophagy protein 5; Involved in autophagic vesicle formation. | 0.999 |
| ATG3 | ATG7 | ENSPTRP00000026253 | ENSPTRP00000079740 | Autophagy-related protein 3. | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] | 0.998 |
| ATG3 | UBL3 | ENSPTRP00000026253 | ENSPTRP00000058837 | Autophagy-related protein 3. | Ubiquitin-like protein. | 0.497 |
| ATG5 | ATG3 | ENSPTRP00000031526 | ENSPTRP00000026253 | Autophagy protein 5; Involved in autophagic vesicle formation. | Autophagy-related protein 3. | 0.999 |
| ATG5 | ATG7 | ENSPTRP00000031526 | ENSPTRP00000079740 | Autophagy protein 5; Involved in autophagic vesicle formation. | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] | 0.998 |
| ATG5 | UBL3 | ENSPTRP00000031526 | ENSPTRP00000058837 | Autophagy protein 5; Involved in autophagic vesicle formation. | Ubiquitin-like protein. | 0.502 |
| ATG7 | ATG3 | ENSPTRP00000079740 | ENSPTRP00000026253 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] | Autophagy-related protein 3. | 0.998 |
| ATG7 | ATG5 | ENSPTRP00000079740 | ENSPTRP00000031526 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] | Autophagy protein 5; Involved in autophagic vesicle formation. | 0.998 |
| ATG7 | HERC5 | ENSPTRP00000079740 | ENSPTRP00000027950 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] | HERC5 isoform 1. | 0.443 |
| ATG7 | UBL3 | ENSPTRP00000079740 | ENSPTRP00000058837 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] | Ubiquitin-like protein. | 0.495 |
| CLPP | ENSPTRP00000081300 | ENSPTRP00000017622 | ENSPTRP00000081300 | ATP-dependent Clp protease proteolytic subunit. | annotation not available | 0.466 |
| CLPP | PIN1 | ENSPTRP00000017622 | ENSPTRP00000017779 | ATP-dependent Clp protease proteolytic subunit. | Peptidyl-prolyl cis-trans isomerase. | 0.466 |
| CLPP | UBL3 | ENSPTRP00000017622 | ENSPTRP00000058837 | ATP-dependent Clp protease proteolytic subunit. | Ubiquitin-like protein. | 0.495 |
| CLPP | UBL5 | ENSPTRP00000017622 | ENSPTRP00000017778 | ATP-dependent Clp protease proteolytic subunit. | Ubiquitin-like 5. | 0.552 |
| ENSPTRP00000081300 | CLPP | ENSPTRP00000081300 | ENSPTRP00000017622 | annotation not available | ATP-dependent Clp protease proteolytic subunit. | 0.466 |
| ENSPTRP00000081300 | UBL3 | ENSPTRP00000081300 | ENSPTRP00000058837 | annotation not available | Ubiquitin-like protein. | 0.500 |
| HERC5 | ATG7 | ENSPTRP00000027950 | ENSPTRP00000079740 | HERC5 isoform 1. | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] | 0.443 |
| HERC5 | UBL3 | ENSPTRP00000027950 | ENSPTRP00000058837 | HERC5 isoform 1. | Ubiquitin-like protein. | 0.599 |
| NEDD8 | SUMO1-2 | ENSPTRP00000090523 | ENSPTRP00000084189 | Ubiquitin-like protein Nedd8. | Small ubiquitin-related modifier. | 0.791 |
| NEDD8 | UBL3 | ENSPTRP00000090523 | ENSPTRP00000058837 | Ubiquitin-like protein Nedd8. | Ubiquitin-like protein. | 0.596 |
