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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C1QAComplement C1q A chain. (245 aa)    
Predicted Functional Partners:
C1QC
Complement C1q C chain.
  
0.999
C1QB
C1QB isoform 2.
  
0.997
C1S
Complement component 1, s subcomponent; Belongs to the peptidase S1 family.
   
 0.983
VSIG4
V-set and immunoglobulin domain containing 4.
   
  
 0.977
C1R
Complement C1r subcomponent heavy chain; C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system; Belongs to the peptidase S1 family.
   
 0.976
SERPING1
Serpin peptidase inhibitor, clade G (C1 inhibitor), member 1; Belongs to the serpin family.
   
 0.973
LOC462577
C4B isoform 1.
   
 
 0.958
CALR
Calreticulin.
   
 0.928
CSF1R
Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
   
  
 0.836
AIF1
Allograft inflammatory factor 1.
   
 
 0.798
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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