SPG7 protein (Pan troglodytes) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

SPG7

Spastic paraplegia 7 (Pure and complicated autosomal recessive). (787 aa)

Predicted Functional Partners:

AFG3L2

0.943

MAIP1

0.886

CSPG5

0.844

PHB2

0.838

TRIM41

0.821

PPIF

0.798

MRPL27

0.770

MRPL13

0.769

MRPS14

0.767

MRPS12

0.766

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFG3L2	MAIP1	ENSPTRP00000016808	ENSPTRP00000021841	AFG3 like matrix AAA peptidase subunit 2.	Matrix AAA peptidase interacting protein 1.	0.714
AFG3L2	MRPL13	ENSPTRP00000016808	ENSPTRP00000035133	AFG3 like matrix AAA peptidase subunit 2.	Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family.	0.769
AFG3L2	MRPL27	ENSPTRP00000016808	ENSPTRP00000015958	AFG3 like matrix AAA peptidase subunit 2.	Mitochondrial ribosomal protein L27.	0.770
AFG3L2	MRPS12	ENSPTRP00000016808	ENSPTRP00000018769	AFG3 like matrix AAA peptidase subunit 2.	Mitochondrial ribosomal protein S12; Belongs to the universal ribosomal protein uS12 family.	0.773
AFG3L2	MRPS14	ENSPTRP00000016808	ENSPTRP00000087170	AFG3 like matrix AAA peptidase subunit 2.	Mitochondrial ribosomal protein S14.	0.767
AFG3L2	PHB2	ENSPTRP00000016808	ENSPTRP00000091437	AFG3 like matrix AAA peptidase subunit 2.	Prohibitin.	0.835
AFG3L2	SPG7	ENSPTRP00000016808	ENSPTRP00000063563	AFG3 like matrix AAA peptidase subunit 2.	Spastic paraplegia 7 (Pure and complicated autosomal recessive).	0.943
CSPG5	SPG7	ENSPTRP00000082765	ENSPTRP00000063563	Chondroitin sulfate proteoglycan 5.	Spastic paraplegia 7 (Pure and complicated autosomal recessive).	0.844
MAIP1	AFG3L2	ENSPTRP00000021841	ENSPTRP00000016808	Matrix AAA peptidase interacting protein 1.	AFG3 like matrix AAA peptidase subunit 2.	0.714
MAIP1	PHB2	ENSPTRP00000021841	ENSPTRP00000091437	Matrix AAA peptidase interacting protein 1.	Prohibitin.	0.692
MAIP1	SPG7	ENSPTRP00000021841	ENSPTRP00000063563	Matrix AAA peptidase interacting protein 1.	Spastic paraplegia 7 (Pure and complicated autosomal recessive).	0.886
MRPL13	AFG3L2	ENSPTRP00000035133	ENSPTRP00000016808	Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family.	AFG3 like matrix AAA peptidase subunit 2.	0.769
MRPL13	MRPL27	ENSPTRP00000035133	ENSPTRP00000015958	Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family.	Mitochondrial ribosomal protein L27.	0.958
MRPL13	MRPS12	ENSPTRP00000035133	ENSPTRP00000018769	Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family.	Mitochondrial ribosomal protein S12; Belongs to the universal ribosomal protein uS12 family.	0.893
MRPL13	MRPS14	ENSPTRP00000035133	ENSPTRP00000087170	Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family.	Mitochondrial ribosomal protein S14.	0.950
MRPL13	PPIF	ENSPTRP00000035133	ENSPTRP00000004647	Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family.	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.435
MRPL13	SPG7	ENSPTRP00000035133	ENSPTRP00000063563	Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family.	Spastic paraplegia 7 (Pure and complicated autosomal recessive).	0.769
MRPL27	AFG3L2	ENSPTRP00000015958	ENSPTRP00000016808	Mitochondrial ribosomal protein L27.	AFG3 like matrix AAA peptidase subunit 2.	0.770
MRPL27	MRPL13	ENSPTRP00000015958	ENSPTRP00000035133	Mitochondrial ribosomal protein L27.	Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family.	0.958
MRPL27	MRPS12	ENSPTRP00000015958	ENSPTRP00000018769	Mitochondrial ribosomal protein L27.	Mitochondrial ribosomal protein S12; Belongs to the universal ribosomal protein uS12 family.	0.969