STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFG3L2AFG3 like matrix AAA peptidase subunit 2. (797 aa)    
Predicted Functional Partners:
TIMMDC1
Translocase of inner mitochondrial membrane domain containing 1.
   
   0.984
SPG7
Spastic paraplegia 7 (Pure and complicated autosomal recessive).
  
 
0.943
NDUFA13
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Involved in the interferon/all-trans-retinoic acid (IFN/RA) induced cell death. This apoptotic activity is inhibited by interaction with viral IRF1. Prevents the transactivation of STAT3 target genes. May play a role in [...]
   
 
 0.862
NDUFA13-2
NADH:ubiquinone oxidoreductase subunit A13.
   
 
 0.862
PHB2
Prohibitin.
   
 0.835
MRPS12
Mitochondrial ribosomal protein S12; Belongs to the universal ribosomal protein uS12 family.
  
 
 0.773
MRPL27
Mitochondrial ribosomal protein L27.
  
 
 0.770
MRPL13
Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family.
  
 
 0.769
MRPS14
Mitochondrial ribosomal protein S14.
   
 
 0.767
DNAJC30
DnaJ (Hsp40) homolog, subfamily C, member 30.
    
 
 0.766
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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