| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| HGS | MVB12A | ENSPTRP00000016628 | ENSPTRP00000065578 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Family with sequence similarity 125, member A. | 0.837 |
| HGS | MVB12B | ENSPTRP00000016628 | ENSPTRP00000036528 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Family with sequence similarity 125, member B. | 0.811 |
| HGS | PDCD6IP | ENSPTRP00000016628 | ENSPTRP00000025415 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Programmed cell death 6 interacting protein. | 0.627 |
| HGS | TSG101 | ENSPTRP00000016628 | ENSPTRP00000062068 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Tumor susceptibility 101. | 0.998 |
| HGS | UBAP1 | ENSPTRP00000016628 | ENSPTRP00000043955 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | UBAP1 isoform 4. | 0.937 |
| HGS | VPS28 | ENSPTRP00000016628 | ENSPTRP00000091027 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | VPS28 subunit of ESCRT-I. | 0.932 |
| HGS | VPS28-2 | ENSPTRP00000016628 | ENSPTRP00000077768 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | VPS28 isoform 16; Belongs to the VPS28 family. | 0.932 |
| HGS | VPS36 | ENSPTRP00000016628 | ENSPTRP00000010034 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Vacuolar protein sorting 36 homolog. | 0.873 |
| HGS | VPS37B | ENSPTRP00000016628 | ENSPTRP00000067422 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Vacuolar protein sorting 37 homolog B. | 0.864 |
| HGS | VPS37C | ENSPTRP00000016628 | ENSPTRP00000063573 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Vacuolar protein sorting 37 homolog C. | 0.780 |
| MVB12A | HGS | ENSPTRP00000065578 | ENSPTRP00000016628 | Family with sequence similarity 125, member A. | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | 0.837 |
| MVB12A | MVB12B | ENSPTRP00000065578 | ENSPTRP00000036528 | Family with sequence similarity 125, member A. | Family with sequence similarity 125, member B. | 0.940 |
| MVB12A | PDCD6IP | ENSPTRP00000065578 | ENSPTRP00000025415 | Family with sequence similarity 125, member A. | Programmed cell death 6 interacting protein. | 0.951 |
| MVB12A | TSG101 | ENSPTRP00000065578 | ENSPTRP00000062068 | Family with sequence similarity 125, member A. | Tumor susceptibility 101. | 0.980 |
| MVB12A | UBAP1 | ENSPTRP00000065578 | ENSPTRP00000043955 | Family with sequence similarity 125, member A. | UBAP1 isoform 4. | 0.868 |
| MVB12A | VPS28 | ENSPTRP00000065578 | ENSPTRP00000091027 | Family with sequence similarity 125, member A. | VPS28 subunit of ESCRT-I. | 0.958 |
| MVB12A | VPS28-2 | ENSPTRP00000065578 | ENSPTRP00000077768 | Family with sequence similarity 125, member A. | VPS28 isoform 16; Belongs to the VPS28 family. | 0.993 |
| MVB12A | VPS36 | ENSPTRP00000065578 | ENSPTRP00000010034 | Family with sequence similarity 125, member A. | Vacuolar protein sorting 36 homolog. | 0.854 |
| MVB12A | VPS37B | ENSPTRP00000065578 | ENSPTRP00000067422 | Family with sequence similarity 125, member A. | Vacuolar protein sorting 37 homolog B. | 0.998 |
| MVB12A | VPS37C | ENSPTRP00000065578 | ENSPTRP00000063573 | Family with sequence similarity 125, member A. | Vacuolar protein sorting 37 homolog C. | 0.989 |
