| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ARHGEF6 | ARHGEF7 | ENSPTRP00000043151 | ENSPTRP00000062187 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6. | Rho guanine nucleotide exchange factor 7. | 0.994 |
| ARHGEF6 | CDC42 | ENSPTRP00000043151 | ENSPTRP00000077648 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6. | Cell division cycle 42 (GTP binding protein, 25kDa). | 0.937 |
| ARHGEF6 | GIT1 | ENSPTRP00000043151 | ENSPTRP00000059492 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6. | G protein-coupled receptor kinase interacting ArfGAP 1. | 0.999 |
| ARHGEF6 | GIT2 | ENSPTRP00000043151 | ENSPTRP00000075299 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6. | G protein-coupled receptor kinase interacting ArfGAP 2. | 0.989 |
| ARHGEF6 | PAK1 | ENSPTRP00000043151 | ENSPTRP00000007058 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6. | Non-specific serine/threonine protein kinase. | 0.998 |
| ARHGEF6 | PAK2 | ENSPTRP00000043151 | ENSPTRP00000027164 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6. | Non-specific serine/threonine protein kinase. | 0.963 |
| ARHGEF6 | PAK3 | ENSPTRP00000043151 | ENSPTRP00000062580 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6. | Serine/threonine-protein kinase PAK 3; Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, or cell cycle regulation. Plays a role in dendrite spine morphogenesis as well as synapse formation and plasticity. Acts as downstream effector of the small GTPases CDC42 and RAC1. Activation by the binding of active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Phosphorylates MAPK4 and MAPK6 and activates the downstrea [...] | 0.994 |
| ARHGEF6 | RAC1 | ENSPTRP00000043151 | ENSPTRP00000068561 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6. | Ras-related C3 botulinum toxin substrate 1 (Rho family, small GTP binding protein Rac1). | 0.971 |
| ARHGEF6 | RAC2 | ENSPTRP00000043151 | ENSPTRP00000069135 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6. | Ras-related C3 botulinum toxin substrate 2 (Rho family, small GTP binding protein Rac2). | 0.959 |
| ARHGEF6 | RAC3 | ENSPTRP00000043151 | ENSPTRP00000024681 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6. | Ras-related C3 botulinum toxin substrate 3 (Rho family, small GTP binding protein Rac3). | 0.962 |
| ARHGEF7 | ARHGEF6 | ENSPTRP00000062187 | ENSPTRP00000043151 | Rho guanine nucleotide exchange factor 7. | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6. | 0.994 |
| ARHGEF7 | CDC42 | ENSPTRP00000062187 | ENSPTRP00000077648 | Rho guanine nucleotide exchange factor 7. | Cell division cycle 42 (GTP binding protein, 25kDa). | 0.995 |
| ARHGEF7 | GIT1 | ENSPTRP00000062187 | ENSPTRP00000059492 | Rho guanine nucleotide exchange factor 7. | G protein-coupled receptor kinase interacting ArfGAP 1. | 0.999 |
| ARHGEF7 | GIT2 | ENSPTRP00000062187 | ENSPTRP00000075299 | Rho guanine nucleotide exchange factor 7. | G protein-coupled receptor kinase interacting ArfGAP 2. | 0.982 |
| ARHGEF7 | PAK1 | ENSPTRP00000062187 | ENSPTRP00000007058 | Rho guanine nucleotide exchange factor 7. | Non-specific serine/threonine protein kinase. | 0.997 |
| ARHGEF7 | PAK2 | ENSPTRP00000062187 | ENSPTRP00000027164 | Rho guanine nucleotide exchange factor 7. | Non-specific serine/threonine protein kinase. | 0.964 |
| ARHGEF7 | PAK3 | ENSPTRP00000062187 | ENSPTRP00000062580 | Rho guanine nucleotide exchange factor 7. | Serine/threonine-protein kinase PAK 3; Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, or cell cycle regulation. Plays a role in dendrite spine morphogenesis as well as synapse formation and plasticity. Acts as downstream effector of the small GTPases CDC42 and RAC1. Activation by the binding of active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Phosphorylates MAPK4 and MAPK6 and activates the downstrea [...] | 0.989 |
| ARHGEF7 | RAC1 | ENSPTRP00000062187 | ENSPTRP00000068561 | Rho guanine nucleotide exchange factor 7. | Ras-related C3 botulinum toxin substrate 1 (Rho family, small GTP binding protein Rac1). | 0.986 |
| ARHGEF7 | RAC2 | ENSPTRP00000062187 | ENSPTRP00000069135 | Rho guanine nucleotide exchange factor 7. | Ras-related C3 botulinum toxin substrate 2 (Rho family, small GTP binding protein Rac2). | 0.969 |
| ARHGEF7 | RAC3 | ENSPTRP00000062187 | ENSPTRP00000024681 | Rho guanine nucleotide exchange factor 7. | Ras-related C3 botulinum toxin substrate 3 (Rho family, small GTP binding protein Rac3). | 0.976 |
