ABCA1 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCA1	APOA1	ENSPTRP00000062700	ENSPTRP00000007404	ATP-binding cassette, sub-family A (ABC1), member 1.	Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility (By similarity).	0.941
ABCA1	APOE	ENSPTRP00000062700	ENSPTRP00000054411	ATP-binding cassette, sub-family A (ABC1), member 1.	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...]	0.763
ABCA1	LCAT	ENSPTRP00000062700	ENSPTRP00000014085	ATP-binding cassette, sub-family A (ABC1), member 1.	Lecithin-cholesterol acyltransferase.	0.728
ABCA1	NR1H2	ENSPTRP00000062700	ENSPTRP00000019472	ATP-binding cassette, sub-family A (ABC1), member 1.	Nuclear receptor subfamily 1, group H, member 2.	0.967
ABCA1	NR1H3	ENSPTRP00000062700	ENSPTRP00000079039	ATP-binding cassette, sub-family A (ABC1), member 1.	Nuclear receptor subfamily 1 group H member 3.	0.913
ABCA1	RAC1	ENSPTRP00000062700	ENSPTRP00000068561	ATP-binding cassette, sub-family A (ABC1), member 1.	Ras-related C3 botulinum toxin substrate 1 (Rho family, small GTP binding protein Rac1).	0.910
ABCA1	RXRA	ENSPTRP00000062700	ENSPTRP00000045122	ATP-binding cassette, sub-family A (ABC1), member 1.	Retinoid X receptor, alpha.	0.789
ABCA1	SCARB1	ENSPTRP00000062700	ENSPTRP00000079498	ATP-binding cassette, sub-family A (ABC1), member 1.	SCARB1 isoform 8; Belongs to the CD36 family.	0.739
ABCA1	SPTLC1	ENSPTRP00000062700	ENSPTRP00000078111	ATP-binding cassette, sub-family A (ABC1), member 1.	Aminotran_1_2 domain-containing protein.	0.734
ABCA1	SREBF2	ENSPTRP00000062700	ENSPTRP00000024869	ATP-binding cassette, sub-family A (ABC1), member 1.	Sterol regulatory element binding transcription factor 2.	0.762
APOA1	ABCA1	ENSPTRP00000007404	ENSPTRP00000062700	Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility (By similarity).	ATP-binding cassette, sub-family A (ABC1), member 1.	0.941
APOA1	APOE	ENSPTRP00000007404	ENSPTRP00000054411	Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility (By similarity).	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...]	0.972
APOA1	LCAT	ENSPTRP00000007404	ENSPTRP00000014085	Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility (By similarity).	Lecithin-cholesterol acyltransferase.	0.963
APOE	ABCA1	ENSPTRP00000054411	ENSPTRP00000062700	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...]	ATP-binding cassette, sub-family A (ABC1), member 1.	0.763
APOE	APOA1	ENSPTRP00000054411	ENSPTRP00000007404	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...]	Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility (By similarity).	0.972
APOE	LCAT	ENSPTRP00000054411	ENSPTRP00000014085	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...]	Lecithin-cholesterol acyltransferase.	0.688
APOE	NR1H2	ENSPTRP00000054411	ENSPTRP00000019472	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...]	Nuclear receptor subfamily 1, group H, member 2.	0.446
APOE	NR1H3	ENSPTRP00000054411	ENSPTRP00000079039	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...]	Nuclear receptor subfamily 1 group H member 3.	0.514
APOE	SCARB1	ENSPTRP00000054411	ENSPTRP00000079498	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...]	SCARB1 isoform 8; Belongs to the CD36 family.	0.626
APOE	SREBF2	ENSPTRP00000054411	ENSPTRP00000024869	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...]	Sterol regulatory element binding transcription factor 2.	0.429