Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABCA4ABCA4 isoform 2. (2282 aa)    
Predicted Functional Partners:
CRYBA1
Crystallin beta A1; Belongs to the beta/gamma-crystallin family.
   
  
 0.766
C2CD3
C2CD3 isoform 3.
      
 0.728
NR1H2
Nuclear receptor subfamily 1, group H, member 2.
    
 0.717
NR1H3
Nuclear receptor subfamily 1 group H member 3.
    
 0.717
SLC24A1
Solute carrier family 24 member 1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
  
 
 0.709
PRPH2
PRPH2 isoform 1.
   
 
 0.706
SLC51B
Solute carrier family 51 beta subunit.
      
 0.692
EYS
EYS isoform 1.
   
 
 0.677
FRMD7
FERM domain containing 7.
      
 0.670
FRMD7-2
FERM domain containing 7.
      
 0.670
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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